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Colloidal nanodispersions for the topical delivery of Ibuprofen: Structure, dynamics and bioperformances
(Elsevier B.V., 2021)
Colloidal liquid-in-liquid nanodispersions such as micro- and nanoemulsions were developed, characterized and compared as potential carriers for the topical administration of ibuprofen. Both colloidal systems were based ...
The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
(MDPI, 2022)
The purpose of this study was to evaluate mechanisms behind the intestinal permeability of minoxidil, with special emphasis on paracellular transport, and elucidate the suitability of minoxidil to be a reference drug for ...
Estimating the Effects of Dental Caries and Its Restorative Treatment on Periodontal Inflammatory and Oxidative Status: A Short Controlled Longitudinal Study
(Frontiers Media S.A., 2021)
Dental caries and periodontitis are among the most common health conditions that are currently recognized as growing socio-economic problems relating to their increasing prevalence, negative socio-economic impact, and ...
Self-limiting interactions in 2D–0D system: A case study of graphene oxide and 12-tungstophosphoric acid nanocomposite
(Elsevier, 2020)
In the present study we investigated the interaction between 12-tungstophosphoric acid (WPA) and graphene oxide (GO) in their nanocomposite by utilizing the loading of WPA as an intrinsic parameter for interaction tuning. ...
Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease
(John Wiley and Sons Inc, 2022)
Aims: GABAergic modulation involved in cognitive processing appears to be substan- tially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric ...
Waste Jute Fabric as a Biosorbent for Heavy Metal Ions from Aqueous Solution
(Korean Fiber Society, 2020)
The influence of the chemical composition on the biosorption potential of waste jute fabric for Ni2+, Cu2+, and Zn2+ was investigated. The raw jute fabric was treated with sodium hydroxide or sodium chlorite to selectively ...
Simultaneous Physico-Mechanical and In Vivo Assessment towards Factual Skin Performance Profile of Topical Polymeric Film-Forming Systems
(MDPI, 2022)
Topical film-forming systems (FFS) change drastically after solvent displacement, therefore indicating their skin metamorphosis/transformation as a property of special regulatory and research interest. This paper deals ...
Biopharmaceutical characterization of rebamipide: The role of mucus binding in regional-dependent intestinal permeability
(Elsevier B.V., 2020)
In this study, we aimed to elucidate biopharmaceutical characteristics of the anti-ulcer drug rebamipide, with special emphasis on the influence of gastrointestinal (GI) mucus on rebamipide segmental-dependent permeability ...
Xenobiotics, trace metals and genetics in the pathogenesis of tauopathies
(MDPI, 2020)
Tauopathies are a disease group characterized by either pathological accumulation or release of fragments of hyperphosphorylated tau proteins originating from the central nervous system. The tau hypotheses of Parkinson’s ...
Pharmacists’ clinical knowledge and practice in the safe use of contraceptives: real knowledge vs. self-perception and the implications
(BioMed Central Ltd, 2021)
Background: Pharmacists are often the first healthcare professionals that patients contact with their illnesses and requests for medical information, which is enhanced following the recent COVID-19 pandemic. Community ...