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Evaluation of ACE inhibitors lipophilicity using in silico and chromatographically obtained hydrophobicity parameters / Procena lipofilnosti ACE inhibitora primenom in silico i hromatografski dobijenih parametara hidrofobnosti
(Savez hemijskih inženjera, Beograd, 2013)
The aim of this study was to compare different calculation methods to determine the lipophilicity, expressed as log P value, of seven ACE inhibitors (enalapril, quinapril, fosinopril, lisinopril, cilazapril, ramipril and ...
Correlation of N-terminal pro-B-type natriuretic peptide with clinical parameters in patients with hypertension
(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2013)
Background/Aim. Identification of patients with arterial hypertension and a possible onset of heart failure by determining the concentration of N-terminal pro-B-type natriuretic peptide (NT-proBNP) enables timely intensification ...
Analysis of regulatory-ethical framework of clinical trials / Analiza razvoja regulatorno-etičkog okvira za klinička ispitivanja
(Srpsko lekarsko društvo, Beograd, 2013)
Introduction. Every clinical trial has to meet all ethical criteria in addition to the scientific ones. The basic ethical principles in the clinical trials are the following: nonmaleficence, beneficence, respect for autonomy ...
Over-expressed CmbT multidrug resistance transporter improves the fitness of Lactococcus lactis / Uticaj povećane ekspresije CmbT MDR transportera na rast Lactococcus lactis
(Društvo genetičara Srbije, Beograd, 2013)
The influence of the over-expression of CmbT multidrug resistance transporter on the growth rate of Lactococcus lactis NZ9000 was studied. L. lactis is a lactic acid bacteria (LAB) widely used as a starter culture in dairy ...
Evaluation of DNA damage in the lymphocytes of young, elderly and Alzheimer's disease patients treated with β-estradiol in the comet assay / Evaluacija oštećenja DNK u limfocitima mladih, starih i pacijenata obolelih od Alchajmerove bolesti tretiranih β-estradiolom u komet testu
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2013)
Background: The antioxidant activity of estrogen has a beneficial impact in Alzheimer's disease. A variety of clinical studies have demonstrated that estrogen replacement therapy in postmenopausal women results in a lower ...
Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection
(Hindawi Publishing Corporation, New York, 2013)
Background. The aim of this study was to examine the novel renal biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) to assist pediatricians in the assessment of longer duration ...
Raman spectroscopy as a new biochemical diagnostic tool / Ramanska spektroskopija kao novo biohemijsko dijagnostičko sredstvo
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2013)
In this review, Raman spectroscopy is described as a new and potentially powerful diagnostic tool in comparison to routine biochemical tests. Advanced instrumentation and new Raman spectroscopy techniques enable rapid and ...
Chemometrically assissted optimization and validation of RP-HPLC method for the analysis of itraconazole and its impurities
(Hrvatsko Farmaceutsko Drustov (HFD)-Croation Pharmaceutical Soc, Zagreb, 2013)
This paper presents the chemometrically assisted optimization and validation of the RP-HPLC method intended for the quantitative analysis of itraconazole and its impurities in pharmaceutical dosage forms. To reach the ...
Apoptosis, annexin a5 and anti-Annexin a5 antibodies in the antiphospholipid syndrome
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2013)
It has been proposed that apoptosis is one of the mechanisms involved in the generation of antiphospholipid antibodies. The presence of antiphospholipid antibodies is the main laboratory criterion for a definite diagnosis ...
Partial Least Square and Hierarchical Clustering in ADMET Modeling: Prediction of Blood - Brain Barrier Permeation of alpha-Adrenergic and Imidazoline Receptor Ligands
(Canadian Soc Pharmaceutical Sciences, Edmonton, 2013)
PURPOSE. Rate of brain penetration (logPS), brain/plasma equilibration rate (logPS-brain), and extent of blood-brain barrier permeation (logBB) of 29 alpha-adrenergic and imidazoline-receptors ligands were examined in ...