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Приказ резултата 11-20 од 55
Fludized hot melt granulation: in situ vs. Spray-on procedure
(Elsevier Science BV, Amsterdam, 2011)
Characteristics of low-density and high-density lipoprotein subclasses in pediatric renal transplant recipients
(Elsevier Science BV, Amsterdam, 2011)
A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells
(Elsevier Science BV, Amsterdam, 2011)
The role of therapeutic drug monitoring in optimazing pharmacotherapy of selected antiepileptics
(Elsevier Science BV, Amsterdam, 2009)
In vitro-in vivo-in silico approach in biopharmaceutical characterization of ibuprofen IR and SR tablets
(Elsevier Science BV, Amsterdam, 2015)
Within the last decades, physiologically based pharmacokinetic models have emerged into a biopharmaceutical toolkit that has been proven useful in understanding how physicochemical, formulation and physiological factors ...
17 beta-carboxamide steroids - in vitro prediction of human skin permeability and retention using PAMPA technique
(Elsevier Science BV, Amsterdam, 2014)
In this paper, twenty-two 17 beta-carboxamide steroids were synthesized from five corticosteroids (hydrocortisone, prednisolone, methylprednisolone, dexamethasone and betamethasone) in two steps. The first step was periodic ...
Sucrose esters as biocompatible surfactants for penetration enhancement: An insight into the mechanism of penetration enhancement studied using stratum corneum model lipids and Langmuir monolayers
(Elsevier Science BV, Amsterdam, 2017)
Up to now, the molecular mechanism of the penetration enhancing effect of sucrose esters (SEs) on stratum corneum (SC) has not been explained in details. In this study, variety of surface sensitive techniques, including ...
In vitro prediction of gastrointestinal absorption of novel beta-hydroxy-beta-arylalkanoic acids using PAMPA technique
(Elsevier Science BV, Amsterdam, 2017)
Prediction of gastrointestinal absorption of thirteen newly synthesized beta-hydroxy-beta-arylalkanoic acids (HAA) and ibuprofen was performed using PAMPA test The highest values of PAMPA parameters (%Tand P-app) were ...
Assessing the potential of solid dispersions to improve dissolution rate and bioavailability of valsartan: In vitro-in silico approach
(Elsevier Science BV, Amsterdam, 2018)
This study aimed to improve dissolution rate of valsartan in an acidic environment and consequently its oral bioavailability by solid dispersion formulation. Valsartan was selected as a model drug due to its low oral ...
Ex vivo skin permeation and penetration of nonivamide from and in vivo skin tolerability of film-forming formulations containing porous silica
(Elsevier Science BV, Amsterdam, 2017)
Aim: The purpose of this study was to evaluate skin permeation and penetration of nonivamide which has been formulated in novel film-forming formulations (FFFs). These formulations aim to prolong the availability of ...