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Spectrophotometric determination of desoximetasone in ointment using 1,4-dihydrazinophthalazine
(Pergamon-Elsevier Science Ltd, Oxford, 1996)
The proposed method is based on coloured hydrazone formation with 1,4-dihydrazinophthalazine as a reagent. Heating at 85 degrees C for 2 h was found necessary to ensure optimal hydrazone formation in the presence of ...
Spectrophotometric determination of nizatidine in pharmaceutical formulations
(Journal of Pharmaceutical and Biomedical Analysis, 1995)
Hydrophilic interaction liquid chromatography in analysis of granisetron HCl and its related substances. Retention mechanisms and method development
(Elsevier Science BV, Amsterdam, 2016)
In this paper separation of granisetron and its two related substances in HILIC mode is presented. Separation was done on silica column derivatized with sulfoalkylbetaine groups (ZIC-HILIC). Firstly, retention mechanisms ...
Quantitation of pregabalin in dried blood spots and dried plasma spots by validated LC-MS/MS methods
(Elsevier Science BV, Amsterdam, 2015)
In this paper, novel LC-MS/MS methods for the determination of antiepileptic drug pregabalin in dried matrix spots (DMS) are presented. This attractive technique of sample collection in micro amount was utilized in the ...
Chaotropic salts in liquid chromatographic method development for the determination of pramipexole and its impurities following quality-by-design principles
(Elsevier Science BV, Amsterdam, 2015)
The aim of this paper is to present a development of liquid chromatographic method when chaotropic salts are used as mobile phase additives following the QbD principles. The effect of critical process parameters (column ...
Analysis of phenolics in wine by high performance thin-layer chromatography with gradient elution and high resolution plate imaging
(Elsevier Science BV, Amsterdam, 2015)
Health benefits of wine, especially with red wine, have been linked to the presence of a wide range of phenolic antioxidants. Thus, the aim of this study was to develop a simple, high performance thin layer chromatographic ...
Spectrophotometric determination of midazolam in pharmaceutical formulations
(Journal of Pharmaceutical and Biomedical Analysis, 1995)
Fluorodensitometric determination of conjugated estrogens in raw material and in pharmaceutical preparations
(Elsevier, 1989)
A simple, rapid and reproducible fluorodensitometric method for the determination of conjugated estrogens has been developed. The proposed procedure includes the following steps: extraction, hydrolysis of sodium sulphate ...
Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms
(Pergamon-Elsevier Science Ltd, Oxford, 1997)
This paper describes a simple densitometric method for the determination of metroprolol tartrate in tablets and ampoules. After separation on silica gel GF254 plates, using acetone-methanol-triethylamine as the mobile phase ...
Application of artificial neural networks in HPLC method development
(Pergamon-Elsevier Science Ltd, Oxford, 1998)
The use of artificial neural networks (ANNs) for response surface modelling in HPLC method development for amiloride and methychlothiazide separation is reported. The independent input variables were pH and methanol ...