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Haematological and iron-related parameters in male and female athletes according to different metabolic energy demands
(Springer, New York, 2011)
We investigated the iron-related haematological parameters in both male and female athletes participating in different sporting disciplines necessitating different metabolic energy demands. A total of 873 athletes (514 ...
Protective role of glutathione reductase in paraquat induced neurotoxicity
(Elsevier Ireland Ltd, Clare, 2012)
Paraquat (PQ), a widely used herbicide is a well-known free radical producing agent. The mechanistic pathways of PQ neurotoxicity were examined by assessing oxidative/nitrosative stress markers. Focus was on the role of ...
Influence of hydrophilic polymers on the complexation of carbamazepine with hydroxypropyl-beta-cyclodextrin
(Elsevier Science BV, Amsterdam, 2015)
In this study binary carbamazepine-hydroxypropyl-beta-cyclodextrin, as well as ternary carbamazepine-hydroxypropyl-beta-cyclodextrin-hydrophilic polymer systems were used to improve dissolution rate of carbamazepine. It ...
DNA Damage in Alzheimer Disease Lymphocytes and Its Relation to Premature Centromere Division
(Karger, Basel, 2013)
While Alzheimer disease (AD) is considered a neurodegenerative disorder, the importance of chromosome instability in non-neuronal cells is equally important, not only for shedding light on the etiology of the disease, but ...
Semisolid self-microemulsifying drug delivery systems (SMEDDSs): Effects on pharmacokinetics of acyclovir in rats
(Elsevier Science BV, Amsterdam, 2018)
Semisolid self-microemulsifying drug delivery system (SMEDDS) with optimized drug loading capacity, stability, dispersibility in aqueous media and in vitro drug release profile, was evaluated in vivo regarding effects on ...
Polyaniline tannate - Synthesis, characterization and electrochemical assessment of superoxide anion radical scavenging activity
(Pergamon-Elsevier Science Ltd, Oxford, 2014)
Polyaniline tannate (PANI-TA) solid microspheres were synthesized by the external-template-free oxidative polymerization of aniline with ammonium peroxydisulfate (APS) in aqueous solution of tannic acid (TA). Syntheses ...
An investigation into the usefulness of different empirical modeling techniques for better control of spray-on fluidized bed melt granulation
(Elsevier Science BV, Amsterdam, 2015)
Melt granulation in fluid bed processors is an emerging technique, but literature data regarding the modeling of this granulation method are lacking. In the present study different techniques (response surface analysis, ...
Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs
(Elsevier Science BV, Amsterdam, 2013)
In the current study, three antiepileptic drugs with zwitterionic properties, namely vigabatrin, pregabalin and gabapentin, were chosen as model analytes to undergo derivatization by applying various n-alkyl chloroformat ...
Investigation of surfactant/cosurfactant synergism impact on ibuprofen solubilization capacity and drug release characteristics of nonionic microemulsions
(Elsevier Science BV, Amsterdam, 2012)
The current study investigates the performances of the multicomponent mixtures of nonionic surfactants regarding the microemulsion stabilisation, drug solubilization and in vitro drug release kinetic. The primary surfactant ...
In Vitro modeling of angiotensin-converting enzyme inhibitor's absorption with chromatographic retention data and selected molecular descriptors
(Elsevier Science BV, Amsterdam, 2014)
Set of nine angiotensin-converting enzyme inhibitors (enalapril, quinapril, fosinopril, lisinopril, cilazapril, ramipril, benazepril, perindopril and moexipril) were studied to evaluate the correlation between their ...