Претраживање
Приказ резултата 1-10 од 43
Distribution of Low-Density Lipoprotein and High-Density Lipoprotein Subclasses in Patients With Sarcoidosis
(Coll Amer Pathologists, Northfield, 2013)
Context.-Systemic inflammatory diseases are associated with proatherogenic lipoprotein profile, but there is a lack of information regarding overall distributions of lipoprotein subclasses in sarcoidosis. Objective.-To ...
Chaotropic agents in liquid chromatographic method development for the simultaneous analysis of levodopa, carbidopa, entacapone and their impurities
(Elsevier Science BV, Amsterdam, 2013)
The simultaneous pharmaceutical analysis of multi-component drugs represents a challenge due to a large total number of analytes present in the sample. These analytes are not only the active pharmaceutical ingredients, but ...
Insights into functional pharmacology of alpha(1) GABA(A) receptors: how much does partial activation at the benzodiazepine site matter?
(Springer, New York, 2013)
Synthesis of ligands inactive or with low activity at alpha(1) GABA(A) receptors has become the key concept for development of novel, more tolerable benzodiazepine (BZ)-like drugs. WYS8, a remarkably (105 times) alpha(1)-subtype ...
Sesquiterpene lactones from the extracts of two Balkan endemic Laserpitium species and their cytotoxic activity
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
Chloroform extracts of the underground parts of two Balkan endemic Laserpitium species, Laserpitium zernyi Hayek and Laserpitium ochridanum Micevski, were chemically investigated. Five unknown guaianolides from the class ...
Effects of physical activity on DNA stability and production of reactive oxygen species
(Wiley-Blackwell, Hoboken, 2013)
Glycogen phosphorylase isoenzyme BB plasma kinetics is not related to myocardial ischemia induced by exercise stress echo test
(Walter de Gruyter Gmbh, Berlin, 2013)
Background: Glycogen phosphorylase BB (GPBB) is released from cardiac cells during myocyte damage. Previous studies have shown contradictory results regarding the relation of enzyme release and reversible myocardial ischemia. ...
Experimental Design in Formulation of Diazepam Nanoemulsions: Physicochemical and Pharmacokinetic Performances
(Wiley-Blackwell, Hoboken, 2013)
With the aid of experimental design, we developed and characterized nanoemulsions for parenteral drug delivery. Formulations containing a mixture of medium-chain triglycerides and soybean oil as oil phase, lecithin ...
Midazolam impairs acquisition and retrieval, but not consolidation of reference memory in the Morris water maze
(Elsevier Science BV, Amsterdam, 2013)
Amnesia is one of the most discussed properties of the benzodiazepine class of drugs. The effects of benzodiazepines on human memory are usually anterograde, while changes in retrograde memory functions were seldom reported. ...
An investigation of diclofenac sodium release from cetylpyridinium chloride-modified natural zeolite as a pharmaceutical excipient
(Elsevier Science BV, Amsterdam, 2013)
In this paper, investigations of zeolite - cationic surfactant - drug composites as drug carriers were performed. For that purpose, after adsorption of the model drug - diclofenac sodium (DS) onto composites obtained by ...
Investigation of adsorption and release of diclofenac sodium by modified zeolites composites
(Elsevier Science BV, Amsterdam, 2013)
Results on adsorption of diclofenac sodium (DS) by modified natural zeolite composites at three levels (10,20 and 30 mmol/100 g) of cationic surfactant-hexadecyltrimethylammonium bromide (HB), in a buffer solution, were ...