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Dissolution assay of theophylline, diprophylline and proxyphylline from a sustained release dosage form by high performance thin layer chromatography
(Biomedical Chromatography, 1992)
The content and dissolution rate of theophylline, diprophylline and proxyphylline from a sustained release formulation were determined by UV in situ densitometry. After separation the chromatographic zones corresponding ...
The influence of β‐cyclodextrin on the solubility and dissolution rate of paracetamol solid dispersions
(Journal of Pharmacy and Pharmacology, 1992)
Abstract— The effect of cyclodextrin (β‐CD) on the solubility and dissolution rate of various paracetamol dispersion powders (1:1 w/w), and tablets was studied. Lower solubility was exhibited by a spray dried solid dispersion ...
Application of artificial neural networks in HPLC method development
(Pergamon-Elsevier Science Ltd, Oxford, 1998)
The use of artificial neural networks (ANNs) for response surface modelling in HPLC method development for amiloride and methychlothiazide separation is reported. The independent input variables were pH and methanol ...
Spectrophotometric investigation of the Pd(II)-quercetin complex in 50% ethanol
(Springer-Verlag Wien, Vienna, 1998)
Composition and stability constant of the Pd(II)-quercetin complex were determined by suitable spectrophotometric methods and pH-metric measurements in 50% Ethanol. It was found that the pd(2+) ion and quercetin form a 1:1 ...
Modification of the rate of aging of diisopropylfluorophosphate-inhibited neuropathy target esterase of hen brain
(Elsevier Sci Ireland Ltd, Clare, 1998)
This study was aimed to investigate the possibility of modifying the rate of aging of diisopropylfluorophosphate-inhibited neuropathy target esterase (NTE) of hen blain. This reaction on NTE occurs with a half-time of 7.4 ...
Use of ANN modelling in structure-retention relationships of diuretics in RP-HPLC
(Pergamon-Elsevier Science Ltd, Oxford, 1999)
Structure-retention relationship study, conducted by RP-HPLC, was used to investigate physical chemical parameters related to the RP retention times of amiloride, hydrochlorothiazide and methyldopa in order to predict the ...
Determination of metal traces in wine by argon stabilized d.c. arc
(Springer Verlag, New York, 1999)
A spetroscopic method for the determination of metal traces (Mn, Cu, Fe) in wine has been developed based on argon stabilized d.c. are plasma at atmospheric pressure. The experimental conditions were optimized using lateral ...
Effect of increasing the bidentate chelate ring size in Co(III) complexes on their behavior in salting-out TLC on different adsorbents
(Springer Hungarica Kiado Kft, Budapest, 1999)
The effect of enlargement of the chelate ring size in Co(III) complexes containing bidentate aminocarboxylato and/or diamine ligands on their R-F values in salting-out chromatography has been investigated on thin layers ...
Spectrophotometric and electrochemical study of protolytic equilibria of some oximes-acetylcholinesterase reactivators
(Pergamon-Elsevier Science Ltd, Oxford, 1999)
Newly synthesized oximes, mono and bis imidazole derivatives, which promise to be more effective acetylcholinesterase reactivators than standard antidotes used, were investigated by spectrophotometric and electrochemical ...
Simple and rapid method for the measurement of nitrite and nitrate in human plasma and cerebrospinal fluid by capillary electrophoresis
(Elsevier Science BV, Amsterdam, 1999)
Nitrite and nitrate levels in physiological fluids are commonly used as an index of nitric oxide production. We developed simple and rapid method for the determination of these anions by capillary zone electrophoresis ...