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Significance of LDL and HDL subclasses characterization in the assessment of risk for colorectal cancer development
(Croatian Soc Medical Biochemists, Zagreb, 2018)
Introduction: Dyslipidaemia contributes to the occurrence of colorectal cancer (CRC). We hypothesized that qualitative changes of lipoproteins are associated with the risk for CRC development. This study analyses low-density ...
Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy
(MDPI, Basel, 2019)
Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons. The aim of the study was to ...
Effects of different carrier materials on physicochemical properties of microencapsulated grape skin extract
(Springer India, New Delhi, 2017)
The goal of this study was to investigate the characteristics of grape skin extract (GSE) spray dried with different carriers: maltodextrin (MD), gum Arabic (GA) and skim milk powder (SMP). The grape skin extract was ...
Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sepsis after Major Abdominal Surgery
(Hindawi Ltd, London, 2018)
Background. The role of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in sepsis after major abdominal surgery and sepsis-associated organ dysfunction is unexplored. Materials ...
Pharmacokinetic Variability of Amikacin After Once-Daily and Twice-Daily Dosing Regimen in Full-Term Neonates
(Japanese Pharmacological Soc, Kyoto, 2014)
The purpose of the study was to compare peak (C-peak) and trough (C-trough) amikacin levels after twice-daily (TD) or once-daily dosing (OD) in full-term neonates. Additionally, the study aimed to address amikacin ...
Role of serotonin in development of esophageal and gastric fundal varices
(Baishideng Publ Grp Co Ltd, Beijing, 2010)
AIM: To determine the effect of free serotonin concentrations in plasma on development of esophageal and gastric fundal varices. METHODS: This prospective study included 33 patients with liver cirrhosis and 24 healthy ...
Assessment of Endothelial Dysfunction: The Role of Symmetrical Dimethylarginine and Proinflammatory Markers in Chronic Kidney Disease and Renal Transplant Recipients
(Hindawi Ltd, London, 2013)
Objectives. The study was designed to evaluate associations between symmetric dimethylarginine (SDMA), inflammation, and superoxide anion (O-2(center dot-)) with endothelial function and to determine their potential for ...
Influence of Solid Drug Delivery System Formulation on Poorly Water-Soluble Drug Dissolution and Permeability
(MDPI, Basel, 2015)
The majority of drugs have a low dissolution rate, which is a limiting step for their absorption. In this manuscript, solid dispersions (SD), solid self-microemulsifying drug delivery systems (S-SMEDDS) and solid ...
Pulmonary function, oxidative stress and inflammatory markers in severe COPD exacerbation
(W B Saunders Co Ltd, London, 2011)
Background: Oxidative stress and inflammation play an important role in the pathogenesis of chronic: obstructive pulmonary disease (COPD). Objective: Pulmonary function, oxidative stress parameters and inflammatory markers ...
Quercetin Ameliorates Experimental Autoimmune Myocarditis in Rats
(Canadian Soc Pharmaceutical Sciences, Edmonton, 2010)
Purpose. Experimental autoimmune myocarditis (EAM) in rats is an animal model of human giant cell myocarditis and post-myocarditis dilated cardiomyopathy. The pathogenesis of EAM has not been elucidated, but there is ...