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Interaction of Lactobacillus fermentum BGHI14 with Rat Colonic Mucosa: Implications for Colitis Induction
(Amer Soc Microbiology, Washington, 2013)
The present study was carried out to test the colonic mucosal response of rats to oral supplementation with Lactobacillus fermentum BGHI14 and to correlate the tissue reaction to trinitrobenzenesulfonate (TNBS)-induced ...
Phenylpropiophenone derivatives as potential anticancer agents: Synthesis, biological evaluation and quantitative structure-activity relationship study
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2013)
Series of twelve chalcone and propafenone derivatives has been synthesized and evaluated for anticancer activities against Hela, Fem-X, PC-3, MCF-7, LS174 and K562 cell lines. The 2D-QSAR and 3D-QSAR studies were performed ...
Changes in LDL and HDL Subclasses in Normal Pregnancy and Associations with Birth Weight, Birth Length and Head Circumference
(Springer/Plenum Publishers, New York, 2013)
Pregnancy is associated with alterations in low-density lipoprotein (LDL) and high-density lipoprotein (HDL) subclasses, but the exact pattern of these variations remains controversial. This study investigates longitudinal ...
Polyaniline and its composites with zeolite ZSM-5 for efficient removal of glyphosate from aqueous solution
(Elsevier Science BV, Amsterdam, 2013)
Nanostructured and granular polyanilines (PANIs) and their composites with zeolite ZSM-5, synthesized by the oxidative polymerization of aniline in water and aqueous solution of sulfuric acid, are evaluated as adsorbents ...
Stepwise optimization approach for improving LC-MS/MS analysis of zwitterionic antiepileptic drugs with implementation of experimental design
(Wiley-Blackwell, Hoboken, 2013)
In this article, a step-by-step optimization procedure for improving analyte response with implementation of experimental design is described. Zwitterionic antiepileptics, namely vigabatrin, pregabalin and gabapentin, were ...
Preparation of carbamazepine-Soluplus (R) solid dispersions by hot-melt extrusion, and prediction of drug-polymer miscibility by thermodynamic model fitting
(Elsevier Science BV, Amsterdam, 2013)
Hot-melt extrusion (HME) is a dust- and solvent-free continuous process enabling the preparation of a variety of solid dosage forms containing solid dispersions of poorly soluble drugs into thermoplastic-polymers. Miscibility ...
Therapeutic Properties of Mushrooms in Managing Adverse Effects in the Metabolic Syndrome
(Bentham Science Publ Ltd, Sharjah, 2013)
Metabolic syndrome (MS) is a modern medical condition characterized by central obesity, hyperglycaemia, hypercholesterolemia and hypertension. The beneficial effects of mushrooms in lowering the symptoms of MS were known ...
The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats
(Elsevier Ireland Ltd, Clare, 2013)
Endocrine-disrupting chemicals currently represent one of the major concerns and this study was aimed to investigate the effects of different doses of cadmium, widespread toxic metal, on the levels of thyroid hormones and ...
Experimental Design in Formulation of Diazepam Nanoemulsions: Physicochemical and Pharmacokinetic Performances
(Wiley-Blackwell, Hoboken, 2013)
With the aid of experimental design, we developed and characterized nanoemulsions for parenteral drug delivery. Formulations containing a mixture of medium-chain triglycerides and soybean oil as oil phase, lecithin ...
Midazolam impairs acquisition and retrieval, but not consolidation of reference memory in the Morris water maze
(Elsevier Science BV, Amsterdam, 2013)
Amnesia is one of the most discussed properties of the benzodiazepine class of drugs. The effects of benzodiazepines on human memory are usually anterograde, while changes in retrograde memory functions were seldom reported. ...