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Potentially Inappropriate Prescribing in Older Primary Care Patients
(Public Library Science, San Francisco, 2014)
Objectives: The aim of the study was to determine the rate of Potentially Inappropriate Medicines (PIM) and Potential Prescription Omissions (PPO) according to Screening Tool of Older Person's potentially inappropriate ...
Medication use in pregnancy: a cross-sectional, multinational web-based study
(BMJ PUBLISHING GROUP, LONDON, 2014)
Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with ...
Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells
(Hindawi Publishing Corp, New York, 2014)
In breast carcinoma, disruption of the p53 pathway is one of the most common genetic alterations. The observation that the p53 can express multiple protein isoforms adds a novel level of complexity to the outcome of p53 ...
Identifying the CmbT substrates specificity by using a quantitative structure-activity relationship (QSAR) study
(Elsevier Science BV, Amsterdam, 2014)
The CmbT substrate specificity and its role as a proton motive force-driven drug efflux pump at a molecular level were investigated in the study. In that order, 3D-quantitative structure-activity relationship (3D-QSAR) ...
Is an integrative laboratory algorithm more effective in detecting alpha-1-antitrypsin deficiency in patients with premature chronic obstructive pulmonary disease than AAT concentration based screening approach?
(Croatian Soc Medical Biochemists, Zagreb, 2014)
Introduction: Alpha-1-antitrypsin deficiency (AATD), genetic risk factor for premature chronic obstructive pulmonary disease (COPD), often remains undetected. The aim of our study was to analyse the effectiveness of an ...
No effect of carbamazepine daily dose on phenobarbital elimination in adult epileptic patients - population pharmacokinetic analysis
(Elsevier Science BV, Amsterdam, 2014)
Subacute toxicity of PCBs in rats: Is hepatic oxidative stress induction dose dependent?
(Elsevier Ireland Ltd, Clare, 2014)
Synthesis of gamma-nitroaldehydes containing quaternary carbon in the alpha-position using a 4-oxalocrotonate tautomerase whole-cell biocatalyst
(Royal Soc Chemistry, Cambridge, 2014)
Synthesis of gamma-nitroaldehydes from branched chain aldehydes and a range of alpha,beta-unsaturated nitroalkenes was achieved by a whole-cell biocatalytic reaction using 4-oxalocrotonate tautomerase as catalyst. Under ...
Biopartitioning micellar chromatography as a predictive tool for skin and corneal permeability of newly synthesized 17 beta-carboxamide steroids
(Elsevier Science BV, Amsterdam, 2014)
In this paper, human skin and corneal permeability of twenty-two newly synthesized 17 beta-carboxamide steroids was predicted using biopartitioning micellar chromatography (BMC). These compounds are potential soft ...