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The role of alpha(1) and alpha(5) subunit-containing GABA(A) receptors in motor impairment induced by benzodiazepines in rats
(Lippincott Williams & Wilkins, Philadelphia, 2012)
Benzodiazepines negatively affect motor coordination and balance and produce myorelaxation. The aim of the present study was to examine the extent to which populations of gamma-aminobutyric acid A (GABA(A)) receptors ...
Direct Spectrophotometric Determination of Hesperidin in Pharmaceutical Preparations
(Slovensko Kemijsko Drustvo, Ljubljana, 2012)
A simple, rapid and reliable direct spectrophotometric method for the determination of hesperidin is proposed and validated. The influence of wavelength, solvent, the ionic strength, pH and temperature on hesperidin ...
Pharmacy network and access to medicines in selected eastern European countries: comparative analysis
(Medicinska Naklada, Zagreb, 2012)
Aim To analyze the pharmacy network (structure and resources) in Bulgaria, Croatia, Serbia, and Slovenia and its relation to public expenditures for medicines. Methods We performed a cross-sectional study using the officially ...
Markers of coagulation activation and enhanced fibrinolysis in Gaucher type 1 patient: Effects of enzyme replacement therapy
(Academic Press Inc Elsevier Science, San Diego, 2012)
A PAMPA Assay as Fast Predictive Model of Passive Human Skin Permeability of New Synthesized Corticosteroid C-21 Esters
(MDPI, Basel, 2012)
The permeation properties of twenty newly synthesized alpha-alkoxyalkanoyl and alpha-aryloxyalkanoyl C-21 esters of standard corticosteroids: Fluocinolone acetonide, dexamethasone, triamcinolone acetonide and hydrocortisone ...
Physicochemical Factors Governing the Partition of Pramipexole and Its Five Impurities in Microemulsion Liquid Chromatographic Systems
(Soc Brasileira Quimica, Sao Paulo, 2012)
Microemulsions when used as mobile phases represent a very powerful chromatographic tool due to their polyphase structure. The aim of this study was to investigate the influence of the mobile phase composition and resulting ...
Simultaneous Analysis of Irbesartan and Hydrochlorothiazide: An Improved HPLC Method with the Aid of a Chemometric Protocol
(MDPI, Basel, 2012)
Experimental design method was used for HPLC determination of irbesartan and hydrochlorothiazide in combined dosage forms. The traditional approach for optimization of experiments is time-consuming, involves a large number ...
Synchronization of the minimal models of bursting neurons coupled by delayed chemical or electrical synapses
(Iop Publishing Ltd, Bristol, 2012)
The minimal two-dimensional model of bursting neuronal dynamics is used to study the influence of time-delay on the properties of synchronization of bursting neurons. Generic properties of bursting and dependence of the ...
Different Potassium Channels are Involved in Relaxation of Rat Renal Artery Induced by P1075
(Wiley, Hoboken, 2012)
The ATP-sensitive K+ channels opener (KATPCO), P1075 [N-cyano-N'-(1,1-dimethylpropyl)-N?-3-pyridylguanidine], has been shown to cause relaxation of various isolated animal and human blood vessels by opening of vascular ...
Agreement between children and parents when reporting anxiety and depressive symptoms in pediatric epilepsy
(Academic Press Inc Elsevier Science, San Diego, 2012)
The levels of agreement between self- and parent/proxy-reports of anxiety and depressive symptoms in pediatric epilepsy were evaluated. Data were drawn from 56 pairs of children with epilepsy and at least one parent. Anxiety ...