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Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats
(Springer Heidelberg, Heidelberg, 2018)
Fully brominated diphenyl ether (BDE-209) is a flame retardant widely used in plastics and textiles. Because of its high persistence, humans are exposed to it continuously, mainly via dust ingestion. We investigated effects ...
Low Fresh Gas Flow Balanced Anesthesia Versus Target Controlled Intravenous Infusion Anesthesia in Laparoscopic Cholecystectomy: A Cost-Minimization Analysis
(Elsevier, Bridgewater, 2008)
Background: Laparoscopic surgery is widely recognized as a well-tolerated and effective method for cholecystectomy. It is also considered cost saving because it has been associated with a decreased hospital length of stay. ...
Optimization and Validation of an RP-HPLC Method for Analysis of Hydrocortisone Acetate and Lidocaine in Suppositories
(AOAC Int, Gaithersburg, 2010)
An RP-HPLC method has been optimized and validated for the simultaneous determination of hydrocortisone acetate and of lidocaine in suppositories. For the method optimization, response surface methodology was applied, and ...
The Antiinflammatory, Gastroprotective and Antioxidant Activities of Hieracium gymnocephalum Extract
(John Wiley & Sons Ltd, Chichester, 2008)
The present study investigated the antiinflammatory, gastroprotective and antioxidant activities of a CH(2)Cl(2) extract of western Balkan endemic Hieracium gymnocephalum Griseb. ex Pant. (Compositae). The carrageenan-induced ...
The stress stability of olanzapine: studies of interactions with excipients in solid state pharmaceutical formulations
(Informa Healthcare, London, 2015)
Stress stability testing represents an important part of the drug development process. It is used as an important tool for the identification of degradation products and degradation pathways, as well as for the assessment ...
Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma lentantha
(Elsevier Gmbh, Urban & Fischer Verlag, Jena, 2006)
The root extracts of Onosma leptanhtha were evaluated for their anti-iflammatory and cytotoxic activities. The cyclohexane extract, which appeared as the most active in both assays, has been further subjected to bioassay-directed ...
Essential oil composition of Anthemis triumfetti (L.) DC.
(Wiley, Hoboken, 2006)
The essential oil of the aerial parts of Anthemis triumfetti (Asteraceae), obtained by hydrodistillation, was analysed by GC and GC-MS; 64 compounds were identified, representing 98.3% of the oil. The major constituents ...
The influence of drug-drug interaction and patients' characteristics on valproic acid's clearance in adults with epilepsy using nonlinear mixed effects modeling
(Elsevier Science BV, Amsterdam, 2009)
Monitoring valproic acid (VPA) concentrations is especially challenging due to its highly variable pharmacokinetics (PK) and complex interactions with other antiepileptic drugs. We used sparse routine therapeutic drug ...
Column high-performance liquid chromatographic determination of norfloxacin and its main impurities in pharmaceuticals
(AOAC Int, Gaithersburg, 2008)
A gradient reversed-phase column high-performance liquid chromatographic method was developed for the detection and quantification of norfloxacin and its major impurities in norfloxacin-containing pharmaceuticals. ...
Soil erodibility in european mountain beech forests
(Canadian Science Publishing, 2021)
Forests in Europe are currently not endangered by soil erosion. However, this can change with climate change or with intensified forest management practices. Using a newly established network of plots in beech forests ...