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Serum paraoxonase (PON1) and its interactions with HDL: Relationship between PON1 and oxidative stress
(Elsevier Inc., 2010)
PON1 is a high density lipoprotein (HDL)-associated serum enzyme. Its primary function is to degrade commonly used insecticides and nerve gases. PON1 is found to be more effective than lecithin:cholesterol acyltransferase ...
Application of artificial neural networks (ANNS) in development of pharmaceutical microemulsions
(Nova Science Publishers, Inc., 2011)
Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation
(Elsevier Inc., 2013)
This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input ...
Computational fluid dynamics: Applications in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter introduces the concept of computational fluid dynamics (CFD) and its applications in pharmaceutical technology. Basic theoretical explanations on the mathematics of fluid flow and numerical grids are provided. ...
The Impact of Urea on the Colloidal Structure of Alkylpolyglucoside-Based Emulsions: Physicochemical and In Vitro In Vivo Characterization
(Wiley-VCH Verlag GMBH, Weinheim, 2011)
Robustness of liquid chromatographic method: How to achieve it and how to confirm it?
(Nova Science Publishers, Inc., 2013)
The quality of liquid chromatographic methods developed for pharmaceutical applications is strongly dependent on their robustness. The robustness issue requires a studious strategy where many important aspects regarding ...
Clinical pharmacokinetic characteristics of novel antiepileptic drugs
(Nova Science Publishers, Inc., 2012)
The choice of an antiepileptic drug (AED) is usually based upon the epileptic seizure type. However, pharmacokinetic (PK) characteristics of AEDs may be valuable support in choosing the optimal therapeutic option for the ...
Abyssomicins: Isolation, properties, and synthesis
(Elsevier B.V., 2013)
The discovery of abyssomicin class of natural products has been the outcome of the search for secondary metabolites possessing inhibitory effect on p-aminobenzoic (pABA) acid biosynthesis, a biosynthetic pathway found in ...
Ibuprofen delivery: Pharmaceutical nanotechnology approach
(Nova Science Publishers, Inc., 2013)
Ibuprofen is non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of pain and inflammation related with rheumatoid arthritis, osteoarthritis, dysmenorrhea, headaches, muscle pain, common cold, after ...
Experimental design application interpretation in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett-Burman design, ...