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Oxidative stress, HDL and atherosclerosis
(Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, 2008)
Oxidative stress is a result of an imbalanced equilibrium between reactive oxygen species (ROS) generation and their elimination by antioxidants. There is substantial evidence indicating that exacerbated oxidative stress ...
The effect of inhibition of nitric oxide synthase on aluminium-induced toxicity in the rat brain
(General Physiol And Biophysics, Bratislava, 2009)
The goal of the present study was to examine the effectiveness of a non-specific nitric oxide synthase (NOS) inhibitor N-nitro-L-arginine methyl ester (L-NAME) to modulate the toxicity of aluminium chloride (AlCl3). Rats ...
Association of oxidative stress and paraoxonase status with PROCAM risk score
(Pergamon-Elsevier Science Ltd, Oxford, 2009)
Objectives: Oxidative stress and paraoxonase activity play a significant role in the pathogenesis of cardiovascular disease (CVD). The Prospective Cardiovascular Munster (PROCAM) study evaluated the prevalence of CVD risk ...
Oxidative stress in the rats brain capillaries in sepsis - The influence of 7-nitroindazole
(Acta Physiologica Hungarica, 2006)
As a part of blood-brain barrier, brain capillaries participate in pathophysiological events during systemic inflammation. We investigated the effects of 7-nitroindazole (7-NI), selective neuronal nitric oxide synthase ...