Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
Osetljivost tri klinička izolata Actinomodura madurae na α-pinen, bioaktivni agens terpentinskog ulja Pinus pinaster
2008
Преузимање 🢃
Аутори
Stojković, D.Soković, Marina
Glamočlija, Jasmina
Džamić, Ana
Ristić, Mihailo
Fahal, A.
Khalid, Sami
Đuić, Ivana
Petrović, Silvana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8 μL/mL, and the minimum microbicidal concentrations (MMCs) were between 100.3 and 150.0 μL/mL. α-Pinene exhibited prominent bioactivity with MICs ranging between 3.3 and 5.0 μL/mL, while its MMC was 10.0 μL/mL against the same clinical isolates. Pinus pinaster turpentine oil and α-pinene might be useful agents in the treatment of mycetoma caused by A. madurae.
Osetljivost tri klinička izolata Actinomadura madurae, najčešćeg izazivača aktinomicetome, testirana je in vitro na terpentinsko ulje dobijeno iz smole Pinus pinaster. Minimalne inhibitorne koncentracije (MIK) ulja bile su 100.3 - 124.8 μL/mL, a minimalne mikrobicidalne koncentracije (MMK) 100.3 - 150.0 μL/mL. α-pinen je pokazao snažnu bioaktivnost, sa vrednostima MIK 3.3 - 5.0 μL/mL, dok je MMK iznosila 10.0 μL/m. Terpentinsko ulje Pinus pinaster i α-pinen mogu biti korisni agensi u tretmanu micetome izazvane taksonom A. madurae.
Кључне речи:
Actionomycetoma / Pinus pinaster / Actinomadura madurae / turpentine oil / α-pinene / antimicrobial activityИзвор:
Archives of Biological Sciences, 2008, 60, 4, 697-701Издавач:
- Srpsko biološko društvo, Beograd, i dr.
Финансирање / пројекти:
- Таксономска, биохемијска и молекуларна истраживања гљива и биолошки активних супстанци (RS-MESTD-MPN2006-2010-143041)
DOI: 10.2298/ABS0804697S
ISSN: 0354-4664
WoS: 000262112000024
Scopus: 2-s2.0-57749092730
Институција/група
PharmacyTY - JOUR AU - Stojković, D. AU - Soković, Marina AU - Glamočlija, Jasmina AU - Džamić, Ana AU - Ristić, Mihailo AU - Fahal, A. AU - Khalid, Sami AU - Đuić, Ivana AU - Petrović, Silvana PY - 2008 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1138 AB - In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8 μL/mL, and the minimum microbicidal concentrations (MMCs) were between 100.3 and 150.0 μL/mL. α-Pinene exhibited prominent bioactivity with MICs ranging between 3.3 and 5.0 μL/mL, while its MMC was 10.0 μL/mL against the same clinical isolates. Pinus pinaster turpentine oil and α-pinene might be useful agents in the treatment of mycetoma caused by A. madurae. AB - Osetljivost tri klinička izolata Actinomadura madurae, najčešćeg izazivača aktinomicetome, testirana je in vitro na terpentinsko ulje dobijeno iz smole Pinus pinaster. Minimalne inhibitorne koncentracije (MIK) ulja bile su 100.3 - 124.8 μL/mL, a minimalne mikrobicidalne koncentracije (MMK) 100.3 - 150.0 μL/mL. α-pinen je pokazao snažnu bioaktivnost, sa vrednostima MIK 3.3 - 5.0 μL/mL, dok je MMK iznosila 10.0 μL/m. Terpentinsko ulje Pinus pinaster i α-pinen mogu biti korisni agensi u tretmanu micetome izazvane taksonom A. madurae. PB - Srpsko biološko društvo, Beograd, i dr. T2 - Archives of Biological Sciences T1 - Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil T1 - Osetljivost tri klinička izolata Actinomodura madurae na α-pinen, bioaktivni agens terpentinskog ulja Pinus pinaster VL - 60 IS - 4 SP - 697 EP - 701 DO - 10.2298/ABS0804697S ER -
@article{ author = "Stojković, D. and Soković, Marina and Glamočlija, Jasmina and Džamić, Ana and Ristić, Mihailo and Fahal, A. and Khalid, Sami and Đuić, Ivana and Petrović, Silvana", year = "2008", abstract = "In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8 μL/mL, and the minimum microbicidal concentrations (MMCs) were between 100.3 and 150.0 μL/mL. α-Pinene exhibited prominent bioactivity with MICs ranging between 3.3 and 5.0 μL/mL, while its MMC was 10.0 μL/mL against the same clinical isolates. Pinus pinaster turpentine oil and α-pinene might be useful agents in the treatment of mycetoma caused by A. madurae., Osetljivost tri klinička izolata Actinomadura madurae, najčešćeg izazivača aktinomicetome, testirana je in vitro na terpentinsko ulje dobijeno iz smole Pinus pinaster. Minimalne inhibitorne koncentracije (MIK) ulja bile su 100.3 - 124.8 μL/mL, a minimalne mikrobicidalne koncentracije (MMK) 100.3 - 150.0 μL/mL. α-pinen je pokazao snažnu bioaktivnost, sa vrednostima MIK 3.3 - 5.0 μL/mL, dok je MMK iznosila 10.0 μL/m. Terpentinsko ulje Pinus pinaster i α-pinen mogu biti korisni agensi u tretmanu micetome izazvane taksonom A. madurae.", publisher = "Srpsko biološko društvo, Beograd, i dr.", journal = "Archives of Biological Sciences", title = "Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil, Osetljivost tri klinička izolata Actinomodura madurae na α-pinen, bioaktivni agens terpentinskog ulja Pinus pinaster", volume = "60", number = "4", pages = "697-701", doi = "10.2298/ABS0804697S" }
Stojković, D., Soković, M., Glamočlija, J., Džamić, A., Ristić, M., Fahal, A., Khalid, S., Đuić, I.,& Petrović, S.. (2008). Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil. in Archives of Biological Sciences Srpsko biološko društvo, Beograd, i dr.., 60(4), 697-701. https://doi.org/10.2298/ABS0804697S
Stojković D, Soković M, Glamočlija J, Džamić A, Ristić M, Fahal A, Khalid S, Đuić I, Petrović S. Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil. in Archives of Biological Sciences. 2008;60(4):697-701. doi:10.2298/ABS0804697S .
Stojković, D., Soković, Marina, Glamočlija, Jasmina, Džamić, Ana, Ristić, Mihailo, Fahal, A., Khalid, Sami, Đuić, Ivana, Petrović, Silvana, "Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil" in Archives of Biological Sciences, 60, no. 4 (2008):697-701, https://doi.org/10.2298/ABS0804697S . .