Study of protolytic, hydrolytic and solubility equilibria of midazolam
Само за регистроване кориснике
1995
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Protolytic equilibria of midazolam in the pH range 0-12 were investigated. Acidity, hydrolysis, equilibrium constants in the heterogeneous system and the solubility of midazolam were determined [I = 0.1 mol l-1 (NaCl), 25 °C]. A spectrophotometric method was developed for the investigation of the mechanism of hydrolysis and the determination of the corresponding equilibrium constants. In addition, buffer characteristics of the two-phase and single-phase midazolam buffers were investigated.
Кључне речи:
Heterogeneous equilibria / Hydrolysis / Midazolam / Protolytic equilibria / Single- and two-phase bufferИзвор:
The Analyst, 1995, 120, 8, 2145-2151Институција/група
PharmacyTY - JOUR AU - Pfendt, Lidija AU - Janjić, T.J AU - Popović, Gordana PY - 1995 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/123 AB - Protolytic equilibria of midazolam in the pH range 0-12 were investigated. Acidity, hydrolysis, equilibrium constants in the heterogeneous system and the solubility of midazolam were determined [I = 0.1 mol l-1 (NaCl), 25 °C]. A spectrophotometric method was developed for the investigation of the mechanism of hydrolysis and the determination of the corresponding equilibrium constants. In addition, buffer characteristics of the two-phase and single-phase midazolam buffers were investigated. T2 - The Analyst T1 - Study of protolytic, hydrolytic and solubility equilibria of midazolam VL - 120 IS - 8 SP - 2145 EP - 2151 DO - 10.1039/AN9952002145 ER -
@article{ author = "Pfendt, Lidija and Janjić, T.J and Popović, Gordana", year = "1995", abstract = "Protolytic equilibria of midazolam in the pH range 0-12 were investigated. Acidity, hydrolysis, equilibrium constants in the heterogeneous system and the solubility of midazolam were determined [I = 0.1 mol l-1 (NaCl), 25 °C]. A spectrophotometric method was developed for the investigation of the mechanism of hydrolysis and the determination of the corresponding equilibrium constants. In addition, buffer characteristics of the two-phase and single-phase midazolam buffers were investigated.", journal = "The Analyst", title = "Study of protolytic, hydrolytic and solubility equilibria of midazolam", volume = "120", number = "8", pages = "2145-2151", doi = "10.1039/AN9952002145" }
Pfendt, L., Janjić, T.J,& Popović, G.. (1995). Study of protolytic, hydrolytic and solubility equilibria of midazolam. in The Analyst, 120(8), 2145-2151. https://doi.org/10.1039/AN9952002145
Pfendt L, Janjić T, Popović G. Study of protolytic, hydrolytic and solubility equilibria of midazolam. in The Analyst. 1995;120(8):2145-2151. doi:10.1039/AN9952002145 .
Pfendt, Lidija, Janjić, T.J, Popović, Gordana, "Study of protolytic, hydrolytic and solubility equilibria of midazolam" in The Analyst, 120, no. 8 (1995):2145-2151, https://doi.org/10.1039/AN9952002145 . .