Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors
Само за регистроване кориснике
2011
Аутори
Stojanov, MarinaStefanović, Aleksandra
Dzingalasević, Gordana
Mandić-Radić, Slavka
Prostran, Milica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Objective: We investigated the relationship between butyrylcholinesterase (BuChE) and cardiovascular risk factors in young male and female. Design and methods: The study comprised 1512 healthy subjects, 18-25 years of age. In fasting sera the concentrations of BuChE and cardiovascular risk factors were estimated. Results: Analysis of variance indicated significant increase in body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL) (p lt 0.05) and albumin (p lt 0.001) with BuChE activity increment in males. In females glucose and albumin (p lt 0.05) increased with BuChE activity. Negative but not significant correlation between BuChE and high-density lipoprotein cholesterol (HDL-C) was detected for both genders. Conclusion: The tendency towards overweight in young male could explain our results on BMI as an independent risk factor for higher BuChE in young male. Glucose as an independent risk factor for higher BuChE activity in females indicates... that BuChE may be a predictor of diabetes.
Кључне речи:
Butyrylcholinesterase / BMI / Glucose / Lipids / LipoproteinsИзвор:
Clinical Biochemistry, 2011, 44, 8-9, 623-626Издавач:
- Pergamon-Elsevier Science Ltd, Oxford
Финансирање / пројекти:
- Базична и клиничко-фармаколошка истраживања механизама дејства и интеракција лекова у нервном и кардиоваскуларном систему (RS-MESTD-Basic Research (BR or ON)-175023)
DOI: 10.1016/j.clinbiochem.2011.03.028
ISSN: 0009-9120
PubMed: 21402063
WoS: 000291081400010
Scopus: 2-s2.0-79955835076
Институција/група
PharmacyTY - JOUR AU - Stojanov, Marina AU - Stefanović, Aleksandra AU - Dzingalasević, Gordana AU - Mandić-Radić, Slavka AU - Prostran, Milica PY - 2011 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1568 AB - Objective: We investigated the relationship between butyrylcholinesterase (BuChE) and cardiovascular risk factors in young male and female. Design and methods: The study comprised 1512 healthy subjects, 18-25 years of age. In fasting sera the concentrations of BuChE and cardiovascular risk factors were estimated. Results: Analysis of variance indicated significant increase in body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL) (p lt 0.05) and albumin (p lt 0.001) with BuChE activity increment in males. In females glucose and albumin (p lt 0.05) increased with BuChE activity. Negative but not significant correlation between BuChE and high-density lipoprotein cholesterol (HDL-C) was detected for both genders. Conclusion: The tendency towards overweight in young male could explain our results on BMI as an independent risk factor for higher BuChE in young male. Glucose as an independent risk factor for higher BuChE activity in females indicates that BuChE may be a predictor of diabetes. PB - Pergamon-Elsevier Science Ltd, Oxford T2 - Clinical Biochemistry T1 - Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors VL - 44 IS - 8-9 SP - 623 EP - 626 DO - 10.1016/j.clinbiochem.2011.03.028 ER -
@article{ author = "Stojanov, Marina and Stefanović, Aleksandra and Dzingalasević, Gordana and Mandić-Radić, Slavka and Prostran, Milica", year = "2011", abstract = "Objective: We investigated the relationship between butyrylcholinesterase (BuChE) and cardiovascular risk factors in young male and female. Design and methods: The study comprised 1512 healthy subjects, 18-25 years of age. In fasting sera the concentrations of BuChE and cardiovascular risk factors were estimated. Results: Analysis of variance indicated significant increase in body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL) (p lt 0.05) and albumin (p lt 0.001) with BuChE activity increment in males. In females glucose and albumin (p lt 0.05) increased with BuChE activity. Negative but not significant correlation between BuChE and high-density lipoprotein cholesterol (HDL-C) was detected for both genders. Conclusion: The tendency towards overweight in young male could explain our results on BMI as an independent risk factor for higher BuChE in young male. Glucose as an independent risk factor for higher BuChE activity in females indicates that BuChE may be a predictor of diabetes.", publisher = "Pergamon-Elsevier Science Ltd, Oxford", journal = "Clinical Biochemistry", title = "Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors", volume = "44", number = "8-9", pages = "623-626", doi = "10.1016/j.clinbiochem.2011.03.028" }
Stojanov, M., Stefanović, A., Dzingalasević, G., Mandić-Radić, S.,& Prostran, M.. (2011). Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors. in Clinical Biochemistry Pergamon-Elsevier Science Ltd, Oxford., 44(8-9), 623-626. https://doi.org/10.1016/j.clinbiochem.2011.03.028
Stojanov M, Stefanović A, Dzingalasević G, Mandić-Radić S, Prostran M. Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors. in Clinical Biochemistry. 2011;44(8-9):623-626. doi:10.1016/j.clinbiochem.2011.03.028 .
Stojanov, Marina, Stefanović, Aleksandra, Dzingalasević, Gordana, Mandić-Radić, Slavka, Prostran, Milica, "Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors" in Clinical Biochemistry, 44, no. 8-9 (2011):623-626, https://doi.org/10.1016/j.clinbiochem.2011.03.028 . .