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Comparative effects of aspirin and NO-releasing aspirins on differentiation, maturation and function of human monocyte-derived dendritic cells in vitro
(Elsevier Science BV, Amsterdam, 2009)
Acetylsalicilyc acid (aspirin, ASA) is a well known anti-inflammatory drug with immunomodulatory properties. NO-releasing aspirins (NO-ASA) are new compounds with anti-inflammatory properties. We studied the effects of ASA ...
Multicriteria optimization methodology in development of HPLC separation of mycophenolic acid and mycophenolic acid glucuronide in human urine and plasma
(Elsevier Science BV, Amsterdam, 2009)
Multicriteria optimization methodology was applied for development of isocratic reversed-phased HPLC method for simultaneous determination of mycophenolic acid (MPA) and mycophenolic acid glucuronide (MPAG) in human urine ...
Dysregulation of T-Cell Development in Adrenal Glucocorticoid-Deprived Rats
(Royal Soc Medicine Press Ltd, London, 2009)
A number of different experimental approaches have been used to elucidate the impact: of basal levels of adrenal gland-derived glucocorticoids (GCs) on T cell development, and thereby T cell-mediated immune responses. ...
Temoporfin-loaded liposomal gels: Viscoelastic properties and in vitro skin penetration
(Elsevier Science BV, Amsterdam, 2009)
Temoporfin (mTHPC) is a potent second-generation photosensitizer. The primary object of this study was to develop a topical mTHPC-loaded liposomal hydrogel able to deliver mTHPC into the stratum corneum (SC) and deeper ...
The influence of cosurfactants and oils on the formation of pharmaceutical microemulsions based on PEG-8 caprylic/capric glycerides
(Elsevier Science BV, Amsterdam, 2008)
In the present study the effect of type and concentration of a cosurfactant and oil on the ability of nonionic surfactant PEG-8 caprylic/capric glycerides (Labrasol (R)) to solubilize both oil and water phases was evaluated. ...
Chemical Composition, Antimicrobial and Antiradical Properties of the Essential Oils of Seseli globiferum Fruits
(Natural Products Inc, Westerville, 2008)
The chemical composition and antimicrobial and antiradical activities of the essential oils isolated from unripe and ripe fruits of S. globiferum Vis. (Apiaceae) have been determined. The most abundant constituent in the ...
Dietary fiber intake of adolescents living in a boarding school in north-eastern part of Serbia: comparison of analyzed and calculated values
(Taylor & Francis Ltd, Abingdon, 2009)
The total fiber intake in the adolescent population living in a boarding school was calculated using weighted food records and food composition tables. Total, insoluble, and soluble fiber daily intakes were also analyzed ...
QSAR study of selective I1-imidazoline receptor ligands
(Taylor & Francis Ltd, Abingdon, 2009)
Selective imidazoline1-receptor (I1-R) ligands are used clinically to reduce blood pressure. Thus, there is significant interest in developing new imidazoline analogs with high selectivity and affinity for I1 receptors. A ...
beta-adrenoceptor blockade ameliorates the clinical course of experimental allergic encephalomyelitis and diminishes its aggravation in adrenalectomized rats
(Elsevier Science BV, Amsterdam, 2007)
As glucocorticoids influence both catecholamine synthesis and adrenoceptor expression by immune cells, the current study was undertaken to distinguish their direct effects on the development of experimental allergic ...
Preparation, characterization and X-ray analysis of [Co-2(Cl)(2)tpmc](BF4)(2). Comparative structural analysis with the complexes having analogous geometries and ligands
(Elsevier Science BV, Amsterdam, 2007)
A novel binuclear Co(II) complex, [Co-2(Cl)(2)tpmc](BF4)(2) (tpmc=N,N,N",N"'-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane), was prepared and structurally characterized by X-ray diffraction analysis at low ...