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Experimental Design in Formulation of Diazepam Nanoemulsions: Physicochemical and Pharmacokinetic Performances
(Wiley-Blackwell, Hoboken, 2013)
With the aid of experimental design, we developed and characterized nanoemulsions for parenteral drug delivery. Formulations containing a mixture of medium-chain triglycerides and soybean oil as oil phase, lecithin ...
The influence of aging and estradiol to progesterone ratio on rat macrophage phenotypic profile and NO and TNF-alpha production
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
The phenotype and function of tissue macrophages substantially depend on the cellular milieu and biological effector molecules, such as steroid hormones, to which they are exposed. Furthermore, in female rats, aging is ...
Route, dose and duration of exposure to cadmium-relevance to oxidative stress induction
(Nova Science Publishers, Inc., 2013)
Cadmium (Cd) is a toxic metal currently ranked as seventh (out of 275) on ATSDR priority list of hazardous substances and it is considered as one of the most important occupational and environmental pollutants. This ...
Spray-dried voriconazole-cyclodextrin complexes: Solubility, dissolution rate and chemical stability
(Elsevier Sci Ltd, Oxford, 2013)
The present work investigates the effect of complexation with hydroxypropyl-beta-cyclodextrin (HPBCD) and 2-O-methyl-beta-cyclodextrin (2-O-MBCD), on voriconazole solubility, dissolution rate and chemical stability. ...
Chaotropic agents in liquid chromatographic method development for the simultaneous analysis of levodopa, carbidopa, entacapone and their impurities
(Elsevier Science BV, Amsterdam, 2013)
The simultaneous pharmaceutical analysis of multi-component drugs represents a challenge due to a large total number of analytes present in the sample. These analytes are not only the active pharmaceutical ingredients, but ...
Seasonal variations in the chemical composition and fatty acid composition of selected fish species from the danube river
(Akademiai Kiado Rt, Budapest, 2013)
The influence of seasonal variations on the chemical composition and composition of fatty acids in five commercially important freshwater fish species from the Danube: white bream, bream, vimba, zope, and Prussian carp, ...
Relative Liver Weight in Rats Subacutely Exposed to Polychlorinated Biphenyls
(NATO Science for Peace and Security Series C: Environmental Security, 2013)
Polychlorinated biphenyls (PCBs) are pollutants abundantly present in the environment. Before they were banned, commercial mixtures of PCBs had been produced in many countries and were used for a number of technical purposes. ...
The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats
(Elsevier Ireland Ltd, Clare, 2013)
Endocrine-disrupting chemicals currently represent one of the major concerns and this study was aimed to investigate the effects of different doses of cadmium, widespread toxic metal, on the levels of thyroid hormones and ...
Medication Use during Pregnancy: A Multinational Perspective
(John Wiley & Sons, Ltd, 2013)
High uric acid and low superoxide dismutase as possible predictors of all-cause and cardiovascular mortality in hemodialysis patients
(Springer, Dordrecht, 2013)
We investigated the role of serum uric acid (sUA) and superoxide dismutase (SOD) as predictive factors for mortality in hemodialysis (HD) patients. SOD, butyrylcholinesterase, and malondialdehyde were estimated ...