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Prikaz rezultata 21-30 od 31
From smart materials to advanced drug delivery systems Preface
(Elsevier Science BV, Amsterdam, 2017)
Characterization of gelation process and drug release profile of thermosensitive liquid lecithin/poloxamer 407 based gels as carriers for percutaneous delivery of ibuprofen
(Elsevier Science BV, Amsterdam, 2015)
Suitability of liquid lecithin (i.e., solution of lecithin in soy bean oil with similar to 60% w/w of phospholipids) for formation of gels, upon addition of water solution of poloxamer 407, was investigated, and formulated ...
Application of miscibility analysis and determination of Soluplus solubility map for development of carvedilol-loaded nanofibers
(Elsevier Science BV, Amsterdam, 2017)
Electrospinning was used to produce carvedilol-loaded Soluplus polymer nanofibers using a systematic approach. Miscibility between drug and polymer was determined through calculation of the interaction parameter, chi, and ...
Investigation of omeprazole stability in oral suspensions for pediatric use prepared extemporaneously from omeprazole capsules
(Elsevier Science BV, Amsterdam, 2016)
An investigation into the usefulness of different empirical modeling techniques for better control of spray-on fluidized bed melt granulation
(Elsevier Science BV, Amsterdam, 2015)
Melt granulation in fluid bed processors is an emerging technique, but literature data regarding the modeling of this granulation method are lacking. In the present study different techniques (response surface analysis, ...
In silico modeling of in situ fluidized bed melt granulation
(Elsevier Science BV, Amsterdam, 2014)
Fluidized bed melt granulation has recently been recognized as a promising technique with numerous advantages over conventional granulation techniques. The aim of this study was to evaluate the possibility of using response ...
Parenteral nanoemulsions of risperidone for enhanced brain delivery in acute psychosis: Physicochemical and in vivo performances
(Elsevier Science BV, Amsterdam, 2017)
This work aimed to deepen the lately acquired knowledge about parenteral nanoemulsions as carriers for brain delivery of risperidone, a poorly water-soluble antipsychotic drug, through establishing the prospective relationship ...
Prediction of aqueous solubility of drug-like molecules using a novel algorithm for automatic adjustment of relative importance of descriptors implemented in counter-propagation artificial neural networks
(Elsevier Science BV, Amsterdam, 2012)
In this work, we present a novel approach for the development of models for prediction of aqueous solubility, based on the implementation of an algorithm for the automatic adjustment of descriptor's relative importance ...
Parenteral nanoemulsions as promising carriers for brain delivery of risperidone: Design, characterization and in vivo pharmacokinetic evaluation
(Elsevier Science BV, Amsterdam, 2015)
This paper describes design and evaluation of parenteral lecithin-based nanoemulsions intended for brain delivery of risperidone, a poorly water-soluble psychopharmacological drug. The nanoemulsions were prepared through ...
Application of miscibility analysis and determination of Soluplus solubility map for development of carvedilol-loaded nanofibers
(Elsevier, 2017)
Electrospinning was used to produce carvedilol-loaded Soluplus polymer nanofibers using a systematic approach. Miscibility between drug and polymer was determined through calculation of the interaction parameter, chi, and ...