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Age and sex determine CD4+ T cell stimulatory and polarizing capacity of rat splenic dendritic cells
(Springer Nature, 2020)
The study investigated influence of sex and age on splenic myeloid dendritic cells (DCs) from Dark Agouti rats. Freshly isolated DCs from young males exhibited less mature phenotype and greater endocytic capacity compared ...
The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
(MDPI, 2022)
The purpose of this study was to evaluate mechanisms behind the intestinal permeability of minoxidil, with special emphasis on paracellular transport, and elucidate the suitability of minoxidil to be a reference drug for ...
Evidence of acute phase reaction in asymptomatic dogs naturally infected with Babesia canis
(Elsevier, 2020)
Asymptomatic outdoor dogs can be carriers of Babesia canis, but data describing the development of an acute phase response (APR) are not available. We hypothesised that these dogs have a moderate APR that could be detected ...
Self-limiting interactions in 2D–0D system: A case study of graphene oxide and 12-tungstophosphoric acid nanocomposite
(Elsevier, 2020)
In the present study we investigated the interaction between 12-tungstophosphoric acid (WPA) and graphene oxide (GO) in their nanocomposite by utilizing the loading of WPA as an intrinsic parameter for interaction tuning. ...
Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease
(John Wiley and Sons Inc, 2022)
Aims: GABAergic modulation involved in cognitive processing appears to be substan- tially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric ...
Waste Jute Fabric as a Biosorbent for Heavy Metal Ions from Aqueous Solution
(Korean Fiber Society, 2020)
The influence of the chemical composition on the biosorption potential of waste jute fabric for Ni2+, Cu2+, and Zn2+ was investigated. The raw jute fabric was treated with sodium hydroxide or sodium chlorite to selectively ...
Simultaneous Physico-Mechanical and In Vivo Assessment towards Factual Skin Performance Profile of Topical Polymeric Film-Forming Systems
(MDPI, 2022)
Topical film-forming systems (FFS) change drastically after solvent displacement, therefore indicating their skin metamorphosis/transformation as a property of special regulatory and research interest. This paper deals ...
Biopharmaceutical characterization of rebamipide: The role of mucus binding in regional-dependent intestinal permeability
(Elsevier B.V., 2020)
In this study, we aimed to elucidate biopharmaceutical characteristics of the anti-ulcer drug rebamipide, with special emphasis on the influence of gastrointestinal (GI) mucus on rebamipide segmental-dependent permeability ...
Xenobiotics, trace metals and genetics in the pathogenesis of tauopathies
(MDPI, 2020)
Tauopathies are a disease group characterized by either pathological accumulation or release of fragments of hyperphosphorylated tau proteins originating from the central nervous system. The tau hypotheses of Parkinson’s ...
Oxidative Stress in Patients before and after On-Pump and Off-Pump Coronary Artery Bypass Grafting: Relationship with Syntax Score
(Hindawi Limited, 2021)
Objective. Coronary artery bypass grafting (CABG) represents the significant source of increased oxidative stress (OS). We aimed to follow the OS status parameters (i.e., ischemia-modified albumin (IMA), malondialdehyde ...