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The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro / Efekat samog paklitaksela, i u kombinaciji sa cikloheksimidom, na učestalost prevremene centromerne deobe in vitro
(Srpsko biološko društvo, Beograd, i dr., 2010)
Premature centromere division (PCD) can be viewed as a manifestation of chromosome instability. In order to evaluate the ability of Paclitaxel (Ptx) and Cycloheximide (Cy) to induce PCD we used a cytokinesis block micronucleus ...
Identification of a rare p.G320R alpha-1-antitrypsin variant in emphysema and lung cancer patients
(Soc Brasil Genetica, Ribeirao Pret, 2010)
The alpha-1-antitrypsin (A1AT) gene is highly polymorphic, with more than 100 genetic variants identified of which some can affect A1AT protein concentration and/or function and lead to pulmonary and/or liver disease. This ...
Oxidation of aniline in the presence of phenolic acids / Oksidativna polimerizacija anilina u prisustvu fenolnih kiselina
(Savez hemijskih inženjera, Beograd, 2010)
Aniline was oxidized with ammonium peroxydisulfate (APS) in aqueous solutions of various phenolic acids: 5-sulfosalicylic acid (SSA), 3,5-dinitrosalicylic acid (DNSA) and gallic acid (GA). Polymerizations were performed ...
Evaluation of different formulas for LDL-C calculation
(BMC, LONDON, 2010)
Background: Friedewald's formula for the estimation of LDL-C concentration is the most often used formula in clinical practice. A recent formula by Anandaraja and colleagues for LDL-C estimation still needs to be evaluated ...
Justification of metformin hydrochloride biowaiver criteria based on bioequivalence study
(ECV-Editio Cantor Verlag Medizin Naturwissenschaften, Aulendorf, 2010)
The Biopharmaceutics Classification System (BCS) represents the framework for predicting the intestinal drug absorption based on its solubility and intestinal permeability. Recent research has lead to the use of in vitro ...
GC-ECD Determination of Lindane and Its Impurity alpha-HCH in Pharmaceutical Products
(Springer Heidelberg, Heidelberg, 2010)
A method was developed to determine lindane (gamma-HCH), the widely used organochlorine pesticide, and its impurity alpha-HCH in bulk and pharmaceutical products (shampoo, gel and emulsion). The system was able to successfully ...
Forced degradation studies of simvastatin using microemulsion liquid chromatography
(Taylor & Francis Inc, Philadelphia, 2010)
In this paper, the definition of simvastatin degradation profile by microemulsion liquid chromatography (MELC) is presented. The aim of the study was to investigate simvastatin stability after various stress tests, such ...
Stability evaluation of temoporfin-loaded liposomal gels for topical application
(Taylor & Francis Ltd, Abingdon, 2010)
Temoporfin (mTHPC) is a potent second-generation synthetic photosensitizer. Topical delivery of mTHPC is of great interest for the photodynamic therapy of psoriasis and superficial skin cancer lesions. The aim of this study ...
Dry sea buckthorn berries (Hippophae rhamnoides L.) - fatty acid and carotene content in pericarp and seed oil
(Drunpp-Sarajevo, Sarajevo, 2010)
Sea buckthorn (Hippophae rhamnoides L., Elaeagnaceae), is a thorny bush or small tree, native to Europe and Asia. Sea buckthorn fruit is rich in oil and carotenes which are found both in pericarp and seeds. Fruit and seed ...
Cationic surfactants-modified natural zeolites: improvement of the excipients functionality
(Informa Healthcare, London, 2010)
Context: In this study an investigation of cationic surfactants-modified natural zeolites as drug formulation excipient was performed. Objective: The aim of this work was to carry out a study of the purified natural zeolitic ...