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Formulation and characterization of nanofibers and films with carvedilol prepared by electrospinning and solution casting method
(Elsevier Science BV, Amsterdam, 2017)
The preparation and characterization of films and nanofibers with carvedilol as a poorly water-soluble drug in poly (ethylene oxide) (PEO) polymer were investigated. Films are prepared by solution casting method, and ...
Synthesis, crystal structures and antimicrobial activity of azido and isocyanato Zn(II) complexes with the condensation product of 2-quinolinecarboxaldehyde and Girard's T reagent
(Taylor & Francis Ltd, Abingdon, 2017)
Two Zn(II) complexes with the condensation product of 2-quinolinecarboxaldehyde and trimethylammonium acetohydrazide chloride (Girard's T reagent) (HLCl) and monodentate pseudohalides (azide and cyanate) have been synthesized ...
Structure-Based Design of Selective Histone Deacetylase 6 Zinc Binding Groups
(Taylor & Francis, 2019)
The binding site of the second catalytic domain of human histone deacetylase 6 (HDAC6 CDII) has structural features that differ from the other human orthologues, being also mainly responsible for the overall enzymatic ...
Implications of oxidative stress in occupational exposure to lead on a cellular level
(Taylor & Francis Ltd, Abingdon, 2015)
The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and ...
Anti-Helicobacter pylori Activity of Four Alchemilla Species (Rosaceae)
(Natural Products Inc, Westerville, 2015)
The present study evaluated the anti-Helicobacter pylori activity of Alchemilla glabra Neygenf. (A. sect. Alchemilla), A. monticola Opiz (A. sect. Plicatae S.E.
Fröhner), A. fissa Günther & Schummel (A. sect. Calycinae ...
Antigenotoxic and antioxidant potential of medicinal mushrooms (Immune Assist) against DNA damage induced by free radicals-an in vitro study
(Elsevier, 2019)
Immune Assist (IA) is produced from extract of six species of medical mushrooms: Agaricus blazei - Cordyceps sinensis - Grifola frondosa - Ganoderma lucidum - Coriolus versicolor - Lentinula edodes. The genoprotective ...
TLC determination of glimepiride and its main impurities in pharmaceuticals
(Taylor & Francis Inc, Philadelphia, 2013)
A quantitative TLC method was developed for the simultaneous separation and quantification of glimepiride and its main degradation impurities, glimepiride-sulfonamide, and glimepiride-carbamate. Chromatographic analysis ...
In vitro and in vivo investigation of taste-masking effectiveness of Eudragit E PO as drug particle coating agent in orally disintegrating tablets
(Taylor & Francis Ltd, Abingdon, 2017)
Context: Considering that bitter taste of drugs incorporated in orally disintegrating tablets (ODTs) can be the main reason for avoiding drug therapy, it is of the utmost importance to achieve successful taste-masking. The ...
Assessing the risk of alcohol-induced dose dumping from sustained-release oral dosage forms: in vitro-in silico approach
(Taylor & Francis Ltd, Abingdon, 2018)
Consumption of alcoholic beverages with sustained-release oral dosage forms may pose a risk to patients due to potential alcohol-induced dose dumping (ADD). Regulatory guidances recommend in vitro dissolution testing to ...
Synthesis, characterization, DFT calculations, and antimicrobial activity of Pd(II) and Co(III) complexes with the condensation derivative of 2-(diphenylphosphino) benzaldehyde and Girard's T reagent
(Taylor & Francis Ltd, Abingdon, 2014)
Complexes of Pd(II) and Co(III) with the condensation derivative of 2-(diphenylphosphino)benzaldehyde and Girard T reagent were synthesized, characterized, and their antimicrobial activities were evaluated. The ligand and ...