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Приказ резултата 11-20 од 69
Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis
(Springer Nature Switzerland, 2020)
Drug-induced Mood- and Cognition-related adverse events (MCAEs) are often only detected during the clinical trial phases of drug development, or even after marketing, thus posing a major safety concern and a challenge for ...
The obesity trends in general population of the republic of Serbia
(Elsevier, 2009)
OBJECTIVES: It is known the obesity increases in general population of the Republic
of Serbia; the average value of the BMI in adults was 26.0 and 26.7 (2000 vs. 2006).
Proposed study, conducted in 2007 had been focused ...
CYP2C19 slow metabolizer phenotype is associated with lower antidepressant efficacy and tolerability
(Elsevier Ireland Ltd, 2022)
The inter-individual variability in CYP2C19-mediated metabolism may affect the antidepressant treatment. The aim of this study is to evaluate differences in antidepressant efficacy and tolerability between different CYP2C19 ...
Nano-and microcarriers as drug delivery systems for usnic acid: Review of literature
(MDPI, 2020)
Usnic acid is one of the most investigated lichen secondary metabolites, with several proven biological properties with potential medical relevance. However, its unfavorable physico-chemical properties, as well as observed ...
Digital light processing (DLP) 3D printing of atomoxetine hydrochloride tablets using photoreactive suspensions
(MDPI AG, 2020)
Three-dimensional (3D) printing technologies are based on successive material printing layer-by-layer and are considered suitable for the production of dosage forms customized for a patient’s needs. In this study, tablets ...
The differential role of alpha(1)- and alpha(5)-containing GABA(A) receptors in mediating diazepam effects on spontaneous locomotor activity and water-maze learning and memory in rats
(Oxford Univ Press, Oxford, 2009)
The clinical use of benzodiazepines (BZs) is hampered by sedation and cognitive deterioration. Although genetic and pharmacological studies suggest that alpha(1)- and alpha(5)-containing GABA(A) receptors mediate and/or ...
Charged aerosol detector response modeling for fatty acids based on experimental settings and molecular features: a machine learning approach
(BioMed Central Ltd, 2021)
The charged aerosol detector (CAD) is the latest representative of aerosol-based detectors that generate a response independent of the analytes’ chemical structure. This study was aimed at accurately predicting the CAD ...
Indicator of antibiotic use in Public pharmacy chain Belgrade
(Elsevier, 2006)
OBJECTIVE: Is to analyze trends in prescription habits and
rational use of antibiotics in different population groups, as well
as expenditure data regarding drug policy changes. METHODS:
We used database from Public ...
Hypolocomotor activity of DIAZEPAM in wistar rats is mediated by Gabaa receptors containing the Alphal, but not the Alpha5 subunit
(Cambridge Univ Press, New York, 2008)
Non-selective and a(5) subunit-selective negative modulators of GABA(A) receptors in a single-day morris water maze task in rats
(Oxford Univ Press, Oxford, 2012)
Objective : It is well known that benzodiazepine binding site ligands
influence learning and memory and that the a5 subunit is significantly
involved in cognition enhancement mediated by the negative modu-
lation of ...