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Modelling in economic evaluations of medicines / Modelovanje u farmakoekonomskim evaluacijama lekova
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Economic evaluation in health (also known as pharmacoeconomic in case of medicines)
identifies, measures, and values costs and outcomes of alternative healthcare technologies, and
can be performed alongside controlled ...
Inhibitors of tumor necrosis factor-α and mechanisms of their action / Inhibitori faktora nekroze tumora–α i mehanizmi njihovog dejstva
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
Tumor necrosis factor (TNF)-α is a proinflammatory cytokine with a role in immunity to pathogens, as well as in the pathogenesis of several autoimmune/inflammatory diseases. Biological drugs targeting this cytokine and ...
Relevance and evaluation of the benchmark dose in toxicology / Značaj i procena benchmark doze u toksikologiji
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
This paper aims to present the importance of the benchmark dose (BMD) as a point of departure (the lowest dose or concentration in the experiment that deviates from the response that differs from the normal ...
Safety and efficacy of interleukin inhibitors in elderly patients with rheumatoid arthritis, psoriasis, and psoriatic arthritis / Bezbednost i efikasnost inhibitora interleukina u terapiji reumatoidnog artritisa, psorijaze i psorijaznog artritisa u populaciji starih osoba
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Elderly patients with rheumatoid arthritis, psoriasis and psoriatic arthritis encompass those with elderly-onset disease, over 60 years of age, but also those with earlier disease onset who entered old age. Considering the ...
Toxicity of Organic and Inorganic Nickel in Pancreatic Cell Cultures: Comparison to Cadmium / Toksičnost organskog i neogranskog nikla u ćelijskim kulturama pankreasa: poređenje sa kadmijumom
(Pharmaceutical Association of Serbia, 2020)
Nickel compounds are Group 1 carcinogens and possibly cancer-causing in the pancreas. We examined the toxicity of nickel in both 2-D and 3-D pancreatic cell cultures, to determine the LD50 for organic and inorganic nickel ...
Spectrophotometric determination of morin in strawberries and their antioxidant activity / Spektrofotometrijsko određivanje sadržaja morina u jagodama i njihove antioksidantne aktivnosti
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Morin is one of the flavonoids with intensive antioxidant activity. With the aim to use its benefits on human health, there is an increasing trend to pay attention to its content in food or supplements. The simplicity ...
Food additives – risk analysis and legislation / Prehrambeni aditivi – analiza rizika i regulativa
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Food additive is any substance not normally consumed as a food, the intentional addition of which to food for a technological purpose results in it or its by-products becoming a component of such foods. The use of each new ...
Assessment of hot-melt coating methods for multiparticulate substrates: mortar-coating vs. pan-coating / Procena metoda za oblaganje višečestičnih supstrata topljenjem - oblaganje u pateni vs. oblaganje u bubnju
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Hot-melt coating (HMC) is an alternative, solvent-free coating method generally used to modify substrate release rate and/or mask its unpleasant taste. The aim of this study was to assess two HMC methods (pan-coating and ...
Medicinal chemistry of histone deacetylase inhibitors / Medicinska hemija inhibitora histon deacetilaza
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Today, we are witnessing an explosion of scientific concepts in cancer chemotherapy. It has been considered for a long time that genetic instability in cancer should be treated with drugs that directly damage the DNA. ...
Concept and utility of population pharmacokinetic and pharmacokinetic/ pharmacodynamic models in drug development and clinical practice / Koncept i upotreba populacionih farmakokinetičkih i farmakokinetičko/farmakodinamičkih modela u razvoju leka i kliničkoj praksi
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Due to frequent clinical trial failures and consequently fewer new drug approvals, the need
for improvement in drug development has, to a certain extent, been met using model-based drug
development. Pharmacometrics is a ...