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Ovarian hormone withdrawal in prepubertal developmental stage does not prevent thymic involution in rats
(Royal Soc Medicine Press Ltd, London, 2013)
The study was undertaken to assess the effects of ovarian hormone withdrawal in prepubertal age on thymopoiesis in 2- (young) and 11-month-old (middle-aged) rats. In ovariectomized (Ox) rats, irrespective of age, thymic ...
Aging affects AO rat splenic conventional dendritic cell subset composition, cytokine synthesis and T-helper polarizing capacity
(Springer, New York, 2013)
It is well-established that almost all cellular components of innate and adaptive immunity undergo age-related remodelling. The findings on age-related changes in both human and mouse dendritic cells (DCs) are conflicting, ...
A retrospective study of vitamin d deficiency in Serbian population
(Walter de Gruyter & Co, Berlin, 2011)
CaNa(2)EDTA chelation attenuates cell damage in workers exposed to lead-a pilot study
(Elsevier Ireland Ltd, Clare, 2015)
Lead induced oxidative cellular damage and long-term persistence of associated adverse effects increases risk of late-onset diseases. CaNa(2)EDTA chelation is known to remove contaminating metals and to reduce free radical ...
Melt granulation in fluidized bed: a comparative study of spray-on versus in situ procedure
(Informa Healthcare, London, 2014)
Objective: The aim of this study was to investigate the influence of process parameters, binder content and binder addition method on characteristics of the granules obtained by melt granulation (MG) in fluidized bed. ...
Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique
(Soc Brasileira Quimica, Sao Paulo, 2012)
Simple and reliable novel methods for the determination of uric acid (UA) are proposed and validated. For quantitative determination of UA, two matrices were used: the Bray-Liebhafsky (BL) oscillatory reaction in a stable ...
Development of a prospective isopropyl alcohol-loaded pharmaceutical base using simultaneous in vitro/in vivo characterization methods of skin performance
(Informa Healthcare, London, 2014)
Context: Approaching of pharmaceutical and cosmetic industries in some aspects inevitably influence formulation of topical pharmaceuticals, urging researchers to introduce novel excipients with proven benefits over traditional ...
Development of a novel RP-HPLC method for the efficient separation of aripiprazole and its nine impurities
(Wiley-VCH Verlag GMBH, Weinheim, 2013)
The development of an RP-HPLC method for the separation of aripiprazole and its nine impurities was performed with the use of partial least squares regression, response surface plot methodology, and chromatographic response ...
Treatment of Venous Ulcers with the Herbal-Based Ointment Herbadermal (R): A Prospective Non-Randomized Pilot Study
(Karger, Basel, 2012)
Background: Venous ulcers (ulcus cruris venosum) are a common chronic disease that requires continuing treatment and significantly influences a patient's way of life. The therapeutic effects of the ointment Herbadermal on ...
Endothelium-dependent vasorelaxant effect of procyanidin B2 on human internal mammary artery
(Elsevier Science BV, Amsterdam, 2017)
The aim of the present study was to investigate and characterize vasorelaxant effect of procyanidin B2 on human internal mammary artery (HIMA) as one of the mechanisms of its protective effect against vascular risk. ...