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Non-coding RNAs in preeclampsia—molecular mechanisms and diagnostic potential
(MDPI, 2021)
Preeclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality worldwide. Defects in trophoblast invasion, differentiation of extravillous trophoblasts and spiral artery remodeling are key factors ...
Multifunctional jute fabrics obtained by different chemical modifications
(Springer Nature B.V., 2020)
Abstract: The aim of the present research is first to reduce the jute fabric non-cellulosic components by using different chemical modifications (i.e. alkali and oxidative) and then to analyze their influence on the jute ...
The role of toxic metals and metalloids in nrf2 signaling
(MDPI AG, 2021)
Nuclear factor erythroid 2-related factor 2 (Nrf2), an emerging regulator of cellular resis-tance to oxidants, serves as one of the key defensive factors against a range of pathological processessuch as oxidative damage, ...
Bcs class iv oral drugs and absorption windows: Regional-dependent intestinal permeability of furosemide
(MDPI AG, 2020)
Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class. While solubility is often ...
H2FPEF score predicts atherosclerosis presence in patients with systemic connective tissue disease
(Wiley Periodicals, 2021)
Background: Cardiovascular diseases are common cause of morbidity and mortality in patients with systemic connective tissue diseases (SCTD) due to accelerated atherosclerosis which couldn't be explained by traditional risk ...
Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous
(Belgrade : Serbian Chemical Society, 2020)
Two new complexes with the general formula [Cu2(L)tpmc](ClO4)3·nH2O (tpmc = N,N′,N′′,N′′′-tetrakis(2-pyridylmethyl)- -1,4,8,11-tetraazacyclotetradecane, L = N-methylglycine, n = 3; L = N,N- -dimethylglycine, ...
Quantitative structure-retention relationships applied to development of liquid chromatography gradient-elution method for the separation of sartans
(Elsevier Science BV, Amsterdam, 2016)
QSRR are mathematically derived relationships between the chromatographic parameters determined for a representative series of analytes in given separation systems and the molecular descriptors accounting for the structural ...
Effects of oral and intraperitoneal magnesium treatment against cadmiuminduced oxidative stress in plasma of rats
(Inst Medical Research & Occupational Health, Zagreb, 2012)
Cadmium (Cd) has been recognised as one of the most important environmental and industrial pollutants, and up-to-date investigations have shown that one of the mechanisms of its toxicity is associated with the induction ...
Thermal properties of 3-hydroxy fatty acids and their binary mixtures as phase change energy storage materials
(John Wiley & Sons, Ltd., 2020)
In the present work, we describe the chemical synthesis of 3-HFAs as prominent derivatives of fatty acids and assess if they could be applied as phase change materials (PCM). In addition, 3-HFAs were obtained by depolymerization ...
Alkyl polyglucoside-based adapalene-loaded microemulsions for targeted dermal delivery: Structure, stability and comparative biopharmaceutical characterization with a conventional dosage form
(Journal of Drug Delivery Science and Technology, 2019)
Aiming to develop biocompatible microemulsions based on natural alkyl polyglucoside surfactant as prospective carriers for improved dermal delivery of adapalene, phase behavior and microstructure of pseudo-ternary oil/decyl ...