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Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation
(Elsevier Inc., 2013)
This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input ...
The antioxidant role of ferritin and transferrin in elite athletes
(Nova Science Publishers, Inc., 2012)
Physical activity has been shown to increase the production of free radicals to a point that can exceed internal protective antioxidant system. The harmful effects of free radicals are neutralized by activity of antioxidant ...
Neural computing in pharmaceutical products and process development
(Elsevier Inc., 2013)
This chapter presents a review of the possible applications of methods based on neural computing in pharmaceutical products and process development. Some of the methods described are used for classification purposes, whereas ...
Experimental design application interpretation in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett-Burman design, ...
Computer-aided formulation development
(Elsevier Inc., 2013)
This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and ...
Chemometric methods application in pharmaceutical products processes analysis control
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on chemometrics and chemometric methods for the analysis of multivariate data. Multivariate data analysis is essential for both product and process development and ...
Artificial neural networks in the optimization of microemulsion liquid chromatography retention and resolution
(Nova Science Publishers, Inc., 2011)
Artificial neural networks (ANNs) present a powerful tool for the modeling of chromatographic retention and resolution as they provide the ability to predict the effects of changes in chosen chromatographic parameters under ...
Ibuprofen delivery: Pharmaceutical nanotechnology approach
(Nova Science Publishers, Inc., 2013)
Ibuprofen is non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of pain and inflammation related with rheumatoid arthritis, osteoarthritis, dysmenorrhea, headaches, muscle pain, common cold, after ...
Computational fluid dynamics: Applications in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter introduces the concept of computational fluid dynamics (CFD) and its applications in pharmaceutical technology. Basic theoretical explanations on the mathematics of fluid flow and numerical grids are provided. ...
Serum paraoxonase (PON1) and its interactions with HDL: Relationship between PON1 and oxidative stress
(Elsevier Inc., 2010)
PON1 is a high density lipoprotein (HDL)-associated serum enzyme. Its primary function is to degrade commonly used insecticides and nerve gases. PON1 is found to be more effective than lecithin:cholesterol acyltransferase ...