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Quantitative structure retention relationship modeling as potential tool in chromatographic determination of stability constants and thermodynamic parameters of β-cyclodextrin complexation process
(Elsevier B.V., 2020)
When cyclodextrins (CDs) are used in chromatography analytes’ retention time is decreased with an in- crease in concentration of CD in the mobile phase. Thus complex stability constants can be determined from the change ...
Comparative chemometric and quantitative structure-retention relationship analysis of anisotropic lipophilicity of 1-arylsuccinimide derivatives determined in high-performance thin-layer chromatography system with aprotic solvents
(Elsevier B.V., 2020)
Numerous structurally different amides and imides including succinimide derivatives exhibit diverse bioactive potential. The development of new compounds requires rationalization in the design in or- der to provide structural ...
Novel computational approaches to retention modeling in dual hydrophilic interactions/reversed phase chromatography
(Elsevier B.V., 2020)
The mixed-mode chromatographic behavior was estimated for imidazoline and serotonin receptor ligands, and their related compounds on dual hydrophilic/reversed phase stationary phase. The Box-Cox transfor- mation was used ...
Performance comparison of nonlinear and linear regression algorithms coupled with different attribute selection methods for quantitative structure - retention relationships modelling in micellar liquid chromatography
(Elsevier, 2020)
In micellar liquid chromatography (MLC), the addition of a surfactant to the mobile phase in excess is accompanied by an alteration of its solubilising capacity and a change in the stationary phase’s properties. As an ...
A comprehensive study on retention of selected model substances in β-cyclodextrin-modified high performance liquid chromatography
(Elsevier B.V., 2021)
The quantitative structure-retention relationship (QSRR) models are not only employed in retention behaviour prediction, but also in an in-depth understanding of complex chromatographic systems. The goal of the present ...
Retention mechanisms of imidazolin and piperazine-related compounds in non-aqueous hydrophilic interaction and supercritical fluid chromatography based on chemometric design and analysis
(Elsevier B.V., 2022)
The experimental design methodology based on central composite design of experiments was applied
to compare the retention mechanisms in supercritical fluid chromatography (SFC) and non-aqueous hy-
drophilic interaction ...