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Relationship between bone resorption, oxidative stress and inflammation in severe COPD exacerbation
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
Background: The natural course of chronic obstructive pulmonary disease (COPD) is complicated by the development of systemic consequences and co-morbidities. Increasing evidence indicates that COPD and osteoporosis are ...
Pulmonary function, oxidative stress and inflammatory markers in severe COPD exacerbation
(W B Saunders Co Ltd, London, 2011)
Background: Oxidative stress and inflammation play an important role in the pathogenesis of chronic: obstructive pulmonary disease (COPD). Objective: Pulmonary function, oxidative stress parameters and inflammatory markers ...
The Association of Serum Iron-Binding Proteins and the Antioxidant Parameter Levels in Age-Related Macular Degeneration
(Taylor & Francis Inc, Philadelphia, 2018)
Purpose: Age-related macular degeneration (AMD) is the leading cause of the irreversible central visual loss among the elderly in the developed countries. Iron is considered a potent generator of the oxidative damage whose ...
Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2
(Springer-Verlag Italia Srl, Milan, 2018)
Xanthine oxidase (XO) is an important enzyme responsible for conversion of purine bases to uric acid and represents the major source of reactive oxygen species (ROS) production in circulation. Since pathophysiological ...
HDL 2 Particles are associated with hyperglycaemia, lower PON1 activity and oxidative stress in type 2 diabetes mellitus patients
(Pergamon-Elsevier Science Ltd, Oxford, 2010)
Objectives: In this study we examined the relationship of oxidative stress and hyperglycaemia to antioxidative capacity of high-density cholesterol (HDL-C) particles in type 2 diabetes mellitus (DM). Design and methods: ...
Paraoxonase activity in athletes with depleted iron stores and iron-deficient erythropoiesis
(Pergamon-Elsevier Science Ltd, Oxford, 2010)
Objective: The aim of this study was to evaluate how conditions that precede anaemia (iron store depletion and iron-deficient erythropoiesis) affect human serum paraoxonase PON1 activity. Design and methods: Based on ...
Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats
(Springer Heidelberg, Heidelberg, 2018)
Fully brominated diphenyl ether (BDE-209) is a flame retardant widely used in plastics and textiles. Because of its high persistence, humans are exposed to it continuously, mainly via dust ingestion. We investigated effects ...
Protective effect of dry olive leaf extract in adrenaline induced DNA damage evaluated using in vitro comet assay with human peripheral leukocytes
(Pergamon-Elsevier Science Ltd, Oxford, 2014)
Excessive release of stress hormone adrenaline is accompanied by generation of reactive oxygen species which may cause disruption of DNA integrity leading to cancer and age-related disorders. Phenolic-rich plant product ...
Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
The purpose of the present study was to determine changes in plasma paraoxonase-1 activity (an indicator of paraoxonase phenotype) throughout normal pregnancy and its relationship with maternal oxidative stress status. The ...
Gender-related reference intervals of urinary 8-oxo-7,8-dihydro-2 '-deoxyguanosine determined by liquid chromatography-tandem mass spectrometry in Serbian population
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
Objectives: Although there are many nucleobase modifications, 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) is one of the dominant form of oxidative modifications of DNA. Urinary 8-oxodG is potentially the best non-invasive ...