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Quality-by-design in pharmaceutical development
(Elsevier Inc., 2013)
This first chapter introduces the concept of quality-by-design (QbD) and its role in pharmaceutical product development. QbD assures the quality of a pharmaceutical product through scientific development and risk management ...
Computer-aided formulation development
(Elsevier Inc., 2013)
This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and ...
Chemometric methods application in pharmaceutical products processes analysis control
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on chemometrics and chemometric methods for the analysis of multivariate data. Multivariate data analysis is essential for both product and process development and ...
Neural computing in pharmaceutical products and process development
(Elsevier Inc., 2013)
This chapter presents a review of the possible applications of methods based on neural computing in pharmaceutical products and process development. Some of the methods described are used for classification purposes, whereas ...
Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation
(Elsevier Inc., 2013)
This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input ...
Experimental design application interpretation in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett-Burman design, ...
Computational fluid dynamics: Applications in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter introduces the concept of computational fluid dynamics (CFD) and its applications in pharmaceutical technology. Basic theoretical explanations on the mathematics of fluid flow and numerical grids are provided. ...