Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets
Само за регистроване кориснике
1998
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablet formulations were compared. Celiprolol hydrochloride and benzylorange react in a 1:1 ratio in the presence of phosphate buffer, producing a yellow, chloroform-extractable ion pair with an absorption maximum at 401 nm. The conditional stability constants were determined by Sommer and Job's method of non-equimolar solutions. The repeatability of the method was tested by analysing Selectol tablets. Spectrophotometric results were compared with those obtained UV-densitometrically on Silica Gel GF 254 plates with acetone-methanol-triethylamine as mobile phase. There was no significant difference in accuracy between the two methods, however the densitometric method was more rapid.
Извор:
Pharmacy and Pharmacology Communications, 1998, 4, 10, 469-471Издавач:
- Wiley
DOI: 10.1111/j.2042-7158.1998.tb00655.x
ISSN: 1460-8081
Scopus: 2-s2.0-0031734647
Институција/група
PharmacyTY - JOUR AU - Vujić, Zorica AU - Radulović, Dušanka PY - 1998 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/203 AB - Spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablet formulations were compared. Celiprolol hydrochloride and benzylorange react in a 1:1 ratio in the presence of phosphate buffer, producing a yellow, chloroform-extractable ion pair with an absorption maximum at 401 nm. The conditional stability constants were determined by Sommer and Job's method of non-equimolar solutions. The repeatability of the method was tested by analysing Selectol tablets. Spectrophotometric results were compared with those obtained UV-densitometrically on Silica Gel GF 254 plates with acetone-methanol-triethylamine as mobile phase. There was no significant difference in accuracy between the two methods, however the densitometric method was more rapid. PB - Wiley T2 - Pharmacy and Pharmacology Communications T1 - Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets VL - 4 IS - 10 SP - 469 EP - 471 DO - 10.1111/j.2042-7158.1998.tb00655.x ER -
@article{ author = "Vujić, Zorica and Radulović, Dušanka", year = "1998", abstract = "Spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablet formulations were compared. Celiprolol hydrochloride and benzylorange react in a 1:1 ratio in the presence of phosphate buffer, producing a yellow, chloroform-extractable ion pair with an absorption maximum at 401 nm. The conditional stability constants were determined by Sommer and Job's method of non-equimolar solutions. The repeatability of the method was tested by analysing Selectol tablets. Spectrophotometric results were compared with those obtained UV-densitometrically on Silica Gel GF 254 plates with acetone-methanol-triethylamine as mobile phase. There was no significant difference in accuracy between the two methods, however the densitometric method was more rapid.", publisher = "Wiley", journal = "Pharmacy and Pharmacology Communications", title = "Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets", volume = "4", number = "10", pages = "469-471", doi = "10.1111/j.2042-7158.1998.tb00655.x" }
Vujić, Z.,& Radulović, D.. (1998). Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets. in Pharmacy and Pharmacology Communications Wiley., 4(10), 469-471. https://doi.org/10.1111/j.2042-7158.1998.tb00655.x
Vujić Z, Radulović D. Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets. in Pharmacy and Pharmacology Communications. 1998;4(10):469-471. doi:10.1111/j.2042-7158.1998.tb00655.x .
Vujić, Zorica, Radulović, Dušanka, "Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets" in Pharmacy and Pharmacology Communications, 4, no. 10 (1998):469-471, https://doi.org/10.1111/j.2042-7158.1998.tb00655.x . .