Приказ основних података о документу
Quantification of coronary artery disease using different modalities of cardiopulmonary exercise testing
dc.creator | Popović, Dejana | |
dc.creator | Guazzi, Marco | |
dc.creator | Jakovljević, Đorđe G. | |
dc.creator | Lasica, Ratko | |
dc.creator | Banović, Marko | |
dc.creator | Ostojić, Miodrag | |
dc.creator | Arena, Ross | |
dc.date.accessioned | 2019-09-02T12:10:22Z | |
dc.date.available | 2019-09-02T12:10:22Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0167-5273 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/3316 | |
dc.description.abstract | Background: This study examined the accuracy of cardiopulmonary exercise testing (CPET) on a treadmill (TM) and recumbent ergometry (RE) in the predicting coronary artery disease (CAD) severity and prognosis. Methods: Forty Caucasian subjects, mean age 63.5 +/- 7.6, with significant coronary artery lesions (>= 50%) were included. Within two months of coronary angiography, TM and RE CPET were performed on two visits 2-4 days apart and subsequently followed up to 32 +/- 10 months. Results: Mean left ventricular ejection fraction was 56.7 +/- 9.6%. TM CPET exhibited a higher occurrence of ST segment depression >= 1 mm (71.05% vs 28.95%, p = 0.04). Subjects with 1-2 stenotic coronary arteries (SCA) demonstrated a better CPET response compared to those with 3-SCA. ROC analysis revealed a high predictive value for the ventilation/carbon dioxide production (VE/VCO2) slope obtained on TM (area 0.84, p = 0.003, Sn 88.9%, Sp 72%) in distinguishing between 1 and 2-SCA and 3-SCA. Among all CPET parameters, work efficiency (Delta VO2/Delta WR) during RE predicted cumulative cardiac events (p lt 0.01). Conclusions: CPET parameters hold predictive value for CAD severity and prognosis. CPET on a TM appears to be more reliable in the quantification of CAD compared to RE. | en |
dc.publisher | Elsevier Ireland Ltd, Clare | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41022/RS// | |
dc.rights | restrictedAccess | |
dc.source | International Journal of Cardiology | |
dc.title | Quantification of coronary artery disease using different modalities of cardiopulmonary exercise testing | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Ласица, Ратко; Гуаззи, Марцо; Поповић, Дејана; Јаковљевић, Ђорђе Г.; Aрена, Росс; Остојић, Миодраг; Бановић, Марко; | |
dc.citation.volume | 285 | |
dc.citation.spage | 11 | |
dc.citation.epage | 13 | |
dc.citation.other | 285: 11-13 | |
dc.citation.rank | M22 | |
dc.identifier.wos | 000464016000003 | |
dc.identifier.doi | 10.1016/j.ijcard.2019.03.012 | |
dc.identifier.pmid | 30879940 | |
dc.identifier.scopus | 2-s2.0-85062809695 | |
dc.type.version | publishedVersion |