Приказ основних података о документу

dc.creatorTulić, Lidija
dc.creatorVidaković, Snežana
dc.creatorTulić, Ivan
dc.creatorĆurčić, Marijana
dc.creatorBulat, Zorica
dc.date.accessioned2019-09-02T12:11:39Z
dc.date.available2019-09-02T12:11:39Z
dc.date.issued2019
dc.identifier.issn0163-4984
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/3359
dc.description.abstractThe aim of this study was to investigate the association of trace element and toxic metal concentrations in blood and the outcome of in vitro fertilization (IVF). The study included 104 consecutive patients that underwent assisted reproductive technology (ART) procedures. The following parameters were determined: cadmium (Cd), mercury (Hg), arsenic (As), and lead (Pb); and copper (Cu), zinc (Zn), selenium (Se), and magnesium (Mg). Serum samples were obtained before commencing stimulation. Patients with smoking habit had significantly higher Pb concentrations (P=0.022), as well as higher concentrations of As and Hg but not significantly. All subjects were divided into groups of pregnant and nonpregnant patients. Pregnant patients had lower mean values of Mg (P=0.009), As (P lt 0.05), and Pb (P=0.034), compared to nonpregnant, and a significant correlation between pregnancy outcome and concentrations of Mg, Cd, and Pb was found. Women who had had delivered had lower Mg (P=0.009) and Cd (P=0.014) concentrations. There was a significant correlation of the negative outcome of IVF procedure with higher concentrations of Pb (P=0.046) and Cd (P=0.012). In conclusion, our results suggest that there is a difference in Mg, Pb, and Cd concentrations between pregnant and nonpregnant women. There was no association between toxic metals and number and quality of oocytes and embryos, while there was with fertilization rate. Concerning trace elements, we did not find the correlation of trace elements with oocyte number and quality, nor with a number of fertilized oocytes, except for Cu. Patients who were pregnant had lower concentrations of Mg.en
dc.publisherHumana Press Inc, Totowa
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46009/RS//
dc.rightsrestrictedAccess
dc.sourceBiological Trace Element Research
dc.subjectIn vitro fertilizationen
dc.subjectPregnancyen
dc.subjectToxic metalsen
dc.subjectTrace elementsen
dc.titleToxic Metal and Trace Element Concentrations in Blood and Outcome of In Vitro Fertilization in Womenen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractБулат, Зорица; Ћурчић, Маријана; Тулић, Лидија; Видаковић, Снежана; Тулић, Иван;
dc.citation.volume188
dc.citation.issue2
dc.citation.spage284
dc.citation.epage294
dc.citation.other188(2): 284-294
dc.citation.rankM23
dc.identifier.wos000461991600006
dc.identifier.doi10.1007/s12011-018-1421-z
dc.identifier.pmid29951726
dc.identifier.scopus2-s2.0-85049115823
dc.type.versionpublishedVersion


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу