Use of palladium(II) chloride as colour-forming reagent in determination of pralidoxime chloride in water and tablets
Само за регистроване кориснике
1988
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Pralidoxime chloride (PAM-2Cl) has been determined spectrophotometrically in Britton-Robinson buffer solution at pH = 6.45; the method is based on measurement of the absorbance of the Pd(II)-pralidoxime complex at 327 nm. Studies of the composition of the complex by Job's continuous variation method, the molar ratio method and Bent-French's method yielded a Pd(II):pralidoxime ratio of 1:1. The conditional stability constant (K′) of the complex at the optimum pH of 6.45 and an ionic strength (μ) of 0.3 M was found to be 105.2. The molar absorptivity was 1.05 × 104 1 mol-1 cm-1. Beer's law was obeyed at concentrations up to 60 μM. The detection limit was 0.55 μg ml-1. The relative standard deviation (N = 10) was 0.28-1.03%. The method was accurate and sensitive for the analysis of PAM-2Cl in water and tablets.
Кључне речи:
compleximetry / palladium(II) chloride / Pralidoxime chloride / spectrophotometry / tablets.Извор:
Journal of Pharmaceutical and Biomedical Analysis, 1988, 6, 6-8, 773-780Институција/група
PharmacyTY - JOUR AU - Karljiković-Rajić, Katarina AU - Stanković, B AU - Granov, A AU - Binenfeld, Z.J. PY - 1988 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/43 AB - Pralidoxime chloride (PAM-2Cl) has been determined spectrophotometrically in Britton-Robinson buffer solution at pH = 6.45; the method is based on measurement of the absorbance of the Pd(II)-pralidoxime complex at 327 nm. Studies of the composition of the complex by Job's continuous variation method, the molar ratio method and Bent-French's method yielded a Pd(II):pralidoxime ratio of 1:1. The conditional stability constant (K′) of the complex at the optimum pH of 6.45 and an ionic strength (μ) of 0.3 M was found to be 105.2. The molar absorptivity was 1.05 × 104 1 mol-1 cm-1. Beer's law was obeyed at concentrations up to 60 μM. The detection limit was 0.55 μg ml-1. The relative standard deviation (N = 10) was 0.28-1.03%. The method was accurate and sensitive for the analysis of PAM-2Cl in water and tablets. T2 - Journal of Pharmaceutical and Biomedical Analysis T1 - Use of palladium(II) chloride as colour-forming reagent in determination of pralidoxime chloride in water and tablets VL - 6 IS - 6-8 SP - 773 EP - 780 DO - 10.1016/0731-7085(88)80090-6 ER -
@article{ author = "Karljiković-Rajić, Katarina and Stanković, B and Granov, A and Binenfeld, Z.J.", year = "1988", abstract = "Pralidoxime chloride (PAM-2Cl) has been determined spectrophotometrically in Britton-Robinson buffer solution at pH = 6.45; the method is based on measurement of the absorbance of the Pd(II)-pralidoxime complex at 327 nm. Studies of the composition of the complex by Job's continuous variation method, the molar ratio method and Bent-French's method yielded a Pd(II):pralidoxime ratio of 1:1. The conditional stability constant (K′) of the complex at the optimum pH of 6.45 and an ionic strength (μ) of 0.3 M was found to be 105.2. The molar absorptivity was 1.05 × 104 1 mol-1 cm-1. Beer's law was obeyed at concentrations up to 60 μM. The detection limit was 0.55 μg ml-1. The relative standard deviation (N = 10) was 0.28-1.03%. The method was accurate and sensitive for the analysis of PAM-2Cl in water and tablets.", journal = "Journal of Pharmaceutical and Biomedical Analysis", title = "Use of palladium(II) chloride as colour-forming reagent in determination of pralidoxime chloride in water and tablets", volume = "6", number = "6-8", pages = "773-780", doi = "10.1016/0731-7085(88)80090-6" }
Karljiković-Rajić, K., Stanković, B., Granov, A.,& Binenfeld, Z.J.. (1988). Use of palladium(II) chloride as colour-forming reagent in determination of pralidoxime chloride in water and tablets. in Journal of Pharmaceutical and Biomedical Analysis, 6(6-8), 773-780. https://doi.org/10.1016/0731-7085(88)80090-6
Karljiković-Rajić K, Stanković B, Granov A, Binenfeld Z. Use of palladium(II) chloride as colour-forming reagent in determination of pralidoxime chloride in water and tablets. in Journal of Pharmaceutical and Biomedical Analysis. 1988;6(6-8):773-780. doi:10.1016/0731-7085(88)80090-6 .
Karljiković-Rajić, Katarina, Stanković, B, Granov, A, Binenfeld, Z.J., "Use of palladium(II) chloride as colour-forming reagent in determination of pralidoxime chloride in water and tablets" in Journal of Pharmaceutical and Biomedical Analysis, 6, no. 6-8 (1988):773-780, https://doi.org/10.1016/0731-7085(88)80090-6 . .