Clinical pharmacology of thyroid and antithyroid drugs
Klinička farmakologija levotiroksina i antitiroidnih lekova
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Autoimmune diseases accompanied by the development of hypothyroidism (Hashimoto's
thyroiditis) and hyperthyroidism (Graves' disease) are one of the most common disorders of the
thyroid gland. Hypothyroidism is a clinical syndrome that occurs as a result of thyroid hormone
deficiency. Hyperthyroidism is excessive activity of the thyroid gland accompanied by
hypersecretion of thyroid hormones. In simple terms, to achieve a euthyroid state in both clinical
syndromes, two drugs are (most commonly) used - levothyroxine (hypothyroidism) and thioamide
(hyperthyroidism). While it may seem simple, during the treatment, which is life-long in the case
of hypothyroidism, patients should actually be carefully monitored, with the adjustment of the
drug dose and the inclusion of other drugs for the treatment of comorbidities.
Najčešća oboljenja štitaste žlezde su autoimune bolesti praćene razvojem hipotiroidizma (Hašimotov tiroiditis) i hipertiroidizma (Grejvsova bolest). Hipotiroidizam je klinički sindrom koji nastaje kao posledica deficita tiroidnih hormona. Hipertiroidizam je preterana aktivnost tiroidne žlezde praćena hipersekrecijom tiroidnih hormona. Pojednostavljeno, za postizanje eutiroidnog stanja u oba klinička sindroma se koriste (najčešće) dva leka - levotiroksin (hipotiroidizam) i tioamid (hipertiroidizam). Naizgled je jednostavno, ali zapravo tokom lečenja, koje je u slučaju hipotiroidizma doživotno, treba pažljivo pratiti pacijente uz prilagođavanje doze leka i uključivanje drugih lekova za lečenje komorbiditeta.
Кључне речи:
Hashimoto's thyroiditis / Graves' disease / levothyroxine / thiamazole / propylthiouracil / Hašimotov tiroiditis / Grejvsova bolest / levotiroksin / tiamazol / propiltiouracilИзвор:
Arhiv za farmaciju, 2022, 72, 5, 444-454Издавач:
- Pharmaceutical Association of Serbia
Институција/група
PharmacyTY - JOUR AU - Stepanović-Petrović, Radica AU - Tomić, Maja PY - 2022 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4405 AB - Autoimmune diseases accompanied by the development of hypothyroidism (Hashimoto's thyroiditis) and hyperthyroidism (Graves' disease) are one of the most common disorders of the thyroid gland. Hypothyroidism is a clinical syndrome that occurs as a result of thyroid hormone deficiency. Hyperthyroidism is excessive activity of the thyroid gland accompanied by hypersecretion of thyroid hormones. In simple terms, to achieve a euthyroid state in both clinical syndromes, two drugs are (most commonly) used - levothyroxine (hypothyroidism) and thioamide (hyperthyroidism). While it may seem simple, during the treatment, which is life-long in the case of hypothyroidism, patients should actually be carefully monitored, with the adjustment of the drug dose and the inclusion of other drugs for the treatment of comorbidities. AB - Najčešća oboljenja štitaste žlezde su autoimune bolesti praćene razvojem hipotiroidizma (Hašimotov tiroiditis) i hipertiroidizma (Grejvsova bolest). Hipotiroidizam je klinički sindrom koji nastaje kao posledica deficita tiroidnih hormona. Hipertiroidizam je preterana aktivnost tiroidne žlezde praćena hipersekrecijom tiroidnih hormona. Pojednostavljeno, za postizanje eutiroidnog stanja u oba klinička sindroma se koriste (najčešće) dva leka - levotiroksin (hipotiroidizam) i tioamid (hipertiroidizam). Naizgled je jednostavno, ali zapravo tokom lečenja, koje je u slučaju hipotiroidizma doživotno, treba pažljivo pratiti pacijente uz prilagođavanje doze leka i uključivanje drugih lekova za lečenje komorbiditeta. PB - Pharmaceutical Association of Serbia T2 - Arhiv za farmaciju T1 - Clinical pharmacology of thyroid and antithyroid drugs T1 - Klinička farmakologija levotiroksina i antitiroidnih lekova VL - 72 IS - 5 SP - 444 EP - 454 DO - 10.5937/arhfarm72-40086 ER -
@article{ author = "Stepanović-Petrović, Radica and Tomić, Maja", year = "2022", abstract = "Autoimmune diseases accompanied by the development of hypothyroidism (Hashimoto's thyroiditis) and hyperthyroidism (Graves' disease) are one of the most common disorders of the thyroid gland. Hypothyroidism is a clinical syndrome that occurs as a result of thyroid hormone deficiency. Hyperthyroidism is excessive activity of the thyroid gland accompanied by hypersecretion of thyroid hormones. In simple terms, to achieve a euthyroid state in both clinical syndromes, two drugs are (most commonly) used - levothyroxine (hypothyroidism) and thioamide (hyperthyroidism). While it may seem simple, during the treatment, which is life-long in the case of hypothyroidism, patients should actually be carefully monitored, with the adjustment of the drug dose and the inclusion of other drugs for the treatment of comorbidities., Najčešća oboljenja štitaste žlezde su autoimune bolesti praćene razvojem hipotiroidizma (Hašimotov tiroiditis) i hipertiroidizma (Grejvsova bolest). Hipotiroidizam je klinički sindrom koji nastaje kao posledica deficita tiroidnih hormona. Hipertiroidizam je preterana aktivnost tiroidne žlezde praćena hipersekrecijom tiroidnih hormona. Pojednostavljeno, za postizanje eutiroidnog stanja u oba klinička sindroma se koriste (najčešće) dva leka - levotiroksin (hipotiroidizam) i tioamid (hipertiroidizam). Naizgled je jednostavno, ali zapravo tokom lečenja, koje je u slučaju hipotiroidizma doživotno, treba pažljivo pratiti pacijente uz prilagođavanje doze leka i uključivanje drugih lekova za lečenje komorbiditeta.", publisher = "Pharmaceutical Association of Serbia", journal = "Arhiv za farmaciju", title = "Clinical pharmacology of thyroid and antithyroid drugs, Klinička farmakologija levotiroksina i antitiroidnih lekova", volume = "72", number = "5", pages = "444-454", doi = "10.5937/arhfarm72-40086" }
Stepanović-Petrović, R.,& Tomić, M.. (2022). Clinical pharmacology of thyroid and antithyroid drugs. in Arhiv za farmaciju Pharmaceutical Association of Serbia., 72(5), 444-454. https://doi.org/10.5937/arhfarm72-40086
Stepanović-Petrović R, Tomić M. Clinical pharmacology of thyroid and antithyroid drugs. in Arhiv za farmaciju. 2022;72(5):444-454. doi:10.5937/arhfarm72-40086 .
Stepanović-Petrović, Radica, Tomić, Maja, "Clinical pharmacology of thyroid and antithyroid drugs" in Arhiv za farmaciju, 72, no. 5 (2022):444-454, https://doi.org/10.5937/arhfarm72-40086 . .