Acid-base equilibria and solubility of verapamil
Апстракт
The intrinsic solubility – S0 (only the neutral form is present in the solution)
and pH-dependent solubility - S (heterogeneous system of neutral and
ionized forms) of verapamil were determined spectrophotometrically. Based
on solubility data pKa value 9.15 of verapamil was indirectly obtained.
Кључне речи:
Solubility / protolytic equilibria / verapamilИзвор:
PHYSICAL CHEMISTRY 2016 (Proceedings) 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia, 2016, II, 797-800Издавач:
- Society of Physical Chemists of Serbia
Финансирање / пројекти:
- Синтеза, квантитативни однос између структуре и дејства, физичко-хемијска карактеризација и анализа фармаколошки активних супстанци (RS-MESTD-Basic Research (BR or ON)-172033)
Напомена:
- 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia
Институција/група
PharmacyTY - CONF AU - Popović, Marija AU - Popović, Gordana AU - Stojadinović, Milica PY - 2016 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5024 AB - The intrinsic solubility – S0 (only the neutral form is present in the solution) and pH-dependent solubility - S (heterogeneous system of neutral and ionized forms) of verapamil were determined spectrophotometrically. Based on solubility data pKa value 9.15 of verapamil was indirectly obtained. PB - Society of Physical Chemists of Serbia C3 - PHYSICAL CHEMISTRY 2016 (Proceedings) 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia T1 - Acid-base equilibria and solubility of verapamil VL - II SP - 797 EP - 800 UR - https://hdl.handle.net/21.15107/rcub_farfar_5024 ER -
@conference{ author = "Popović, Marija and Popović, Gordana and Stojadinović, Milica", year = "2016", abstract = "The intrinsic solubility – S0 (only the neutral form is present in the solution) and pH-dependent solubility - S (heterogeneous system of neutral and ionized forms) of verapamil were determined spectrophotometrically. Based on solubility data pKa value 9.15 of verapamil was indirectly obtained.", publisher = "Society of Physical Chemists of Serbia", journal = "PHYSICAL CHEMISTRY 2016 (Proceedings) 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia", title = "Acid-base equilibria and solubility of verapamil", volume = "II", pages = "797-800", url = "https://hdl.handle.net/21.15107/rcub_farfar_5024" }
Popović, M., Popović, G.,& Stojadinović, M.. (2016). Acid-base equilibria and solubility of verapamil. in PHYSICAL CHEMISTRY 2016 (Proceedings) 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia Society of Physical Chemists of Serbia., II, 797-800. https://hdl.handle.net/21.15107/rcub_farfar_5024
Popović M, Popović G, Stojadinović M. Acid-base equilibria and solubility of verapamil. in PHYSICAL CHEMISTRY 2016 (Proceedings) 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia. 2016;II:797-800. https://hdl.handle.net/21.15107/rcub_farfar_5024 .
Popović, Marija, Popović, Gordana, Stojadinović, Milica, "Acid-base equilibria and solubility of verapamil" in PHYSICAL CHEMISTRY 2016 (Proceedings) 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia, II (2016):797-800, https://hdl.handle.net/21.15107/rcub_farfar_5024 .