3D printing of carvedilol oral dosage forms using selective laser sintering technique

Abstract

The adjustment of the dose according to the individual needs of the patient is a unique advantage of 3D printing technology, which is of particular importance for the pediatric and geriatric population, due to the diverse needs and characteristics of these groups of patients (Kotta et al., 2018). Selective laser sintering (SLS) is one of the newest 3D printing techniques that uses powder materials, where the powder particles are connected under the influence of laser beams. The main disadvantage of SLS 3D printing is the high process temperature, which can lead to the degradation of active substances. On the other hand, this technique has many advantages, such as high resolution, the possibility of powder recycling and the absence of pre- processing (Fina et al., 2018; Thakkar et al., 2021).