Assesing virulence potential of Acinetobacter baumannii isolates recovered from COVID-19 patients
Аутори
Filipić, BrankicaNovović, Katarina
Kuzmanović Nedeljković, Snežana
Jovčić, Branko
Kojić, Milan
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
BACKGROUND
From the start of COVID-19 pandemic, many patients suffering severe clinical presentation of COVID-19 and
acute respiratory failure have been administered to intensive care units (ICUs). Need for noninvasive or invasive
mechanical ventilation represents a high-risk factor for these patients to develop Acinetobacter baumannii
superinfection.
OBJECTIVES
The main goal of this study was to examine virulence potential of A. baumannii isolates recovered from
COVID-19 patients admitted to ICU as well as to compare differences in virulence among isolates originated
from male and female patients or from different sample types.
METHODS
64 A. baumannii isolates were recovered from COVID-19 patients from December 2020 to February 2021.
The isolates were originated from different sample types: blood, tip of the central venous catheter, tracheal
aspirate, tip of the aspirator and sputum. Genetic relatedness of ApaI digested A. baumannii isolates,
was determined by pul...sed-field gel electrophoresis (PFGE). Affinity to mucin binding was tested using in vitro
model and isolates were examined for two types of motilities: swarming and twitching.
Кључне речи:
Virulence potential / Acinetobacter Baumannii / ICU / COVID-19Извор:
FEMS Conference on Microbiology in association with Serbian Society of Microbiology, 30 June - 2 July 2022, Serbia - electronic abstract book, 2022, 96-96Издавач:
- Federation of European Microbiological Societies
- Serbian Society for Microbiology
Институција/група
PharmacyTY - CONF AU - Filipić, Brankica AU - Novović, Katarina AU - Kuzmanović Nedeljković, Snežana AU - Jovčić, Branko AU - Kojić, Milan PY - 2022 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5118 AB - BACKGROUND From the start of COVID-19 pandemic, many patients suffering severe clinical presentation of COVID-19 and acute respiratory failure have been administered to intensive care units (ICUs). Need for noninvasive or invasive mechanical ventilation represents a high-risk factor for these patients to develop Acinetobacter baumannii superinfection. OBJECTIVES The main goal of this study was to examine virulence potential of A. baumannii isolates recovered from COVID-19 patients admitted to ICU as well as to compare differences in virulence among isolates originated from male and female patients or from different sample types. METHODS 64 A. baumannii isolates were recovered from COVID-19 patients from December 2020 to February 2021. The isolates were originated from different sample types: blood, tip of the central venous catheter, tracheal aspirate, tip of the aspirator and sputum. Genetic relatedness of ApaI digested A. baumannii isolates, was determined by pulsed-field gel electrophoresis (PFGE). Affinity to mucin binding was tested using in vitro model and isolates were examined for two types of motilities: swarming and twitching. PB - Federation of European Microbiological Societies PB - Serbian Society for Microbiology C3 - FEMS Conference on Microbiology in association with Serbian Society of Microbiology, 30 June - 2 July 2022, Serbia - electronic abstract book T1 - Assesing virulence potential of Acinetobacter baumannii isolates recovered from COVID-19 patients SP - 96 EP - 96 UR - https://hdl.handle.net/21.15107/rcub_farfar_5118 ER -
@conference{ author = "Filipić, Brankica and Novović, Katarina and Kuzmanović Nedeljković, Snežana and Jovčić, Branko and Kojić, Milan", year = "2022", abstract = "BACKGROUND From the start of COVID-19 pandemic, many patients suffering severe clinical presentation of COVID-19 and acute respiratory failure have been administered to intensive care units (ICUs). Need for noninvasive or invasive mechanical ventilation represents a high-risk factor for these patients to develop Acinetobacter baumannii superinfection. OBJECTIVES The main goal of this study was to examine virulence potential of A. baumannii isolates recovered from COVID-19 patients admitted to ICU as well as to compare differences in virulence among isolates originated from male and female patients or from different sample types. METHODS 64 A. baumannii isolates were recovered from COVID-19 patients from December 2020 to February 2021. The isolates were originated from different sample types: blood, tip of the central venous catheter, tracheal aspirate, tip of the aspirator and sputum. Genetic relatedness of ApaI digested A. baumannii isolates, was determined by pulsed-field gel electrophoresis (PFGE). Affinity to mucin binding was tested using in vitro model and isolates were examined for two types of motilities: swarming and twitching.", publisher = "Federation of European Microbiological Societies, Serbian Society for Microbiology", journal = "FEMS Conference on Microbiology in association with Serbian Society of Microbiology, 30 June - 2 July 2022, Serbia - electronic abstract book", title = "Assesing virulence potential of Acinetobacter baumannii isolates recovered from COVID-19 patients", pages = "96-96", url = "https://hdl.handle.net/21.15107/rcub_farfar_5118" }
Filipić, B., Novović, K., Kuzmanović Nedeljković, S., Jovčić, B.,& Kojić, M.. (2022). Assesing virulence potential of Acinetobacter baumannii isolates recovered from COVID-19 patients. in FEMS Conference on Microbiology in association with Serbian Society of Microbiology, 30 June - 2 July 2022, Serbia - electronic abstract book Federation of European Microbiological Societies., 96-96. https://hdl.handle.net/21.15107/rcub_farfar_5118
Filipić B, Novović K, Kuzmanović Nedeljković S, Jovčić B, Kojić M. Assesing virulence potential of Acinetobacter baumannii isolates recovered from COVID-19 patients. in FEMS Conference on Microbiology in association with Serbian Society of Microbiology, 30 June - 2 July 2022, Serbia - electronic abstract book. 2022;:96-96. https://hdl.handle.net/21.15107/rcub_farfar_5118 .
Filipić, Brankica, Novović, Katarina, Kuzmanović Nedeljković, Snežana, Jovčić, Branko, Kojić, Milan, "Assesing virulence potential of Acinetobacter baumannii isolates recovered from COVID-19 patients" in FEMS Conference on Microbiology in association with Serbian Society of Microbiology, 30 June - 2 July 2022, Serbia - electronic abstract book (2022):96-96, https://hdl.handle.net/21.15107/rcub_farfar_5118 .