Spectrophotometric quantification of quercetine using a micelle system

Abstract

ABSTRACT The current research provides the development of the new spectrophotometric method for the simple and affordable quercetin quantification. Proposed method based on formation of supramolecular assembles of quercetin (Q) and cetyl trimethylammonium bromide (CTAB). Under selected experimental conditions (l = 378 nm, cCTAB = 2 mM and T = 25 °C), Beer’s law was obeyed in the quercetin concentration ranged 2 ¥10-6 - 8¥10-5 mol dm-3. The method sensitivity was 2.1 × 104 dm2 mol–1 (the molar absorptivity) as well as 1¥10-6 mol dm-3 (the limit of detection). The method applicability to the direct Q determination in a pharmaceutical formulation (Quercetin+C capsules, Twinlab) was demonstrated.