Assessment of polyphenol content and in vitro antioxidant potential of wild growing and cultured raspberry leaf
Аутори
Pavlović, DraganaVukelić-Nikolić, Marija
Marčetić, Mirjana
Kitić, Dušanka
Kostić, Milica
Milutinović, Milica
Miladinović, Bojana
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Rubus idaeus L., folium (raspberry leaf) is according to EMA/HMPC
monograph indicated as traditional herbal medicinal product for: the symptomatic
relief of minor spasm associated with menstrual periods, the symptomatic treatment
of mild inflammation in the mouth or throat and the symptomatic treatment of mild
diarrhea. The aim of this work was quantitative determination of phenolic compounds
(namely: total polyphenols, tannins, flavonoids, arbutin and hydroquinone) and
antioxidant capacity of the different leaves extracts of wild and cultivated Rubus
ideus. Total polyphenols, tannins and flavonoids were determined
spectrophotometrically, HPLC method was employed for quantification of arbutin
and hydroquinone. DPPH test was used for fast antioxidant screening. Arbutin and
hydroquinone were absent in all samples despite some literature date on arbutin
presence in Rubus idaeus. Our phytochemical study showed that raspberry leaves
extracts contain significant amounts of polyph...enolic compounds, which could be
useful in its quality estimation. Cultured raspberry leaf extracts seem to be reacher
source of this secondary metabolites while hydromethanolic extracts of wild growing
plant material exhibited the strongest antioxidant activity. Polyphenolic content and
demonstrated activity could, at least in part, explain pharmacological effects of
raspberry leaves.
Кључне речи:
Rubus idaeus / phenolics / arbutin / hydroquinoneИзвор:
13th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, 20th to 23th June, 2019 - Book of Abstracts, 2019, 178-178Издавач:
- Department of Biology and Ecology, Faculty of Sciences and Mathematics, University of Niš
- Institute for Nature Conservation of Serbia
Финансирање / пројекти:
- Превентивни, терапијски и етички приступ преклиничким и клиничким истраживањима гена и модулатора редокс ћелијске сигнализације у имунском, инфламаторном и пролиферативном одговору ћелије (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41018)
- Традиционални и нови производи од плодова гајених и самониклих врста воћака и винове лозе и нус-продуката у преради, са посебним освртом на аутохтоне сорте: хемијска карактеризација и биолошки профил (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46013)
Напомена:
- 13th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, Stara planina Mt., 20th to 23th June 2019
Институција/група
PharmacyTY - CONF AU - Pavlović, Dragana AU - Vukelić-Nikolić, Marija AU - Marčetić, Mirjana AU - Kitić, Dušanka AU - Kostić, Milica AU - Milutinović, Milica AU - Miladinović, Bojana PY - 2019 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5305 AB - Rubus idaeus L., folium (raspberry leaf) is according to EMA/HMPC monograph indicated as traditional herbal medicinal product for: the symptomatic relief of minor spasm associated with menstrual periods, the symptomatic treatment of mild inflammation in the mouth or throat and the symptomatic treatment of mild diarrhea. The aim of this work was quantitative determination of phenolic compounds (namely: total polyphenols, tannins, flavonoids, arbutin and hydroquinone) and antioxidant capacity of the different leaves extracts of wild and cultivated Rubus ideus. Total polyphenols, tannins and flavonoids were determined spectrophotometrically, HPLC method was employed for quantification of arbutin and hydroquinone. DPPH test was used for fast antioxidant screening. Arbutin and hydroquinone were absent in all samples despite some literature date on arbutin presence in Rubus idaeus. Our phytochemical study showed that raspberry leaves extracts contain significant amounts of polyphenolic compounds, which could be useful in its quality estimation. Cultured raspberry leaf extracts seem to be reacher source of this secondary metabolites while hydromethanolic extracts of wild growing plant material exhibited the strongest antioxidant activity. Polyphenolic content and demonstrated activity could, at least in part, explain pharmacological effects of raspberry leaves. PB - Department of Biology and Ecology, Faculty of Sciences and Mathematics, University of Niš PB - Institute for Nature Conservation of Serbia C3 - 13th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, 20th to 23th June, 2019 - Book of Abstracts T1 - Assessment of polyphenol content and in vitro antioxidant potential of wild growing and cultured raspberry leaf SP - 178 EP - 178 UR - https://hdl.handle.net/21.15107/rcub_farfar_5305 ER -
@conference{ author = "Pavlović, Dragana and Vukelić-Nikolić, Marija and Marčetić, Mirjana and Kitić, Dušanka and Kostić, Milica and Milutinović, Milica and Miladinović, Bojana", year = "2019", abstract = "Rubus idaeus L., folium (raspberry leaf) is according to EMA/HMPC monograph indicated as traditional herbal medicinal product for: the symptomatic relief of minor spasm associated with menstrual periods, the symptomatic treatment of mild inflammation in the mouth or throat and the symptomatic treatment of mild diarrhea. The aim of this work was quantitative determination of phenolic compounds (namely: total polyphenols, tannins, flavonoids, arbutin and hydroquinone) and antioxidant capacity of the different leaves extracts of wild and cultivated Rubus ideus. Total polyphenols, tannins and flavonoids were determined spectrophotometrically, HPLC method was employed for quantification of arbutin and hydroquinone. DPPH test was used for fast antioxidant screening. Arbutin and hydroquinone were absent in all samples despite some literature date on arbutin presence in Rubus idaeus. Our phytochemical study showed that raspberry leaves extracts contain significant amounts of polyphenolic compounds, which could be useful in its quality estimation. Cultured raspberry leaf extracts seem to be reacher source of this secondary metabolites while hydromethanolic extracts of wild growing plant material exhibited the strongest antioxidant activity. Polyphenolic content and demonstrated activity could, at least in part, explain pharmacological effects of raspberry leaves.", publisher = "Department of Biology and Ecology, Faculty of Sciences and Mathematics, University of Niš, Institute for Nature Conservation of Serbia", journal = "13th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, 20th to 23th June, 2019 - Book of Abstracts", title = "Assessment of polyphenol content and in vitro antioxidant potential of wild growing and cultured raspberry leaf", pages = "178-178", url = "https://hdl.handle.net/21.15107/rcub_farfar_5305" }
Pavlović, D., Vukelić-Nikolić, M., Marčetić, M., Kitić, D., Kostić, M., Milutinović, M.,& Miladinović, B.. (2019). Assessment of polyphenol content and in vitro antioxidant potential of wild growing and cultured raspberry leaf. in 13th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, 20th to 23th June, 2019 - Book of Abstracts Department of Biology and Ecology, Faculty of Sciences and Mathematics, University of Niš., 178-178. https://hdl.handle.net/21.15107/rcub_farfar_5305
Pavlović D, Vukelić-Nikolić M, Marčetić M, Kitić D, Kostić M, Milutinović M, Miladinović B. Assessment of polyphenol content and in vitro antioxidant potential of wild growing and cultured raspberry leaf. in 13th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, 20th to 23th June, 2019 - Book of Abstracts. 2019;:178-178. https://hdl.handle.net/21.15107/rcub_farfar_5305 .
Pavlović, Dragana, Vukelić-Nikolić, Marija, Marčetić, Mirjana, Kitić, Dušanka, Kostić, Milica, Milutinović, Milica, Miladinović, Bojana, "Assessment of polyphenol content and in vitro antioxidant potential of wild growing and cultured raspberry leaf" in 13th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, 20th to 23th June, 2019 - Book of Abstracts (2019):178-178, https://hdl.handle.net/21.15107/rcub_farfar_5305 .