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Applicability of Expert System for Drug Development as a tool for co-processed excipients formulation development
dc.creator | Vasiljević, Ivana | |
dc.creator | Turković, Erna | |
dc.creator | Ibrić, Svetlana | |
dc.creator | Vasiljević, Dragana | |
dc.creator | Parojčić, Jelena | |
dc.date.accessioned | 2023-12-05T17:07:45Z | |
dc.date.available | 2023-12-05T17:07:45Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 1409 - 8695 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/5318 | |
dc.description.abstract | Expert System for Drug Development, i.e. SeDeM Expert System (Span. Sistema Experto para DEsarrollo de Medicamentos) represents a method intended for evaluation of powder properties affecting processability, particularly compression behavior (Pérez et al., 2006). Additionally, it is recognized as useful formulation tool, since it provides identification of impaired powder properties and facilitates formulation development suitable for direct compression, based on mathematical equations. Relevant parameters described in SeDeM Expert System are divided into 5 groups and denoted as “incidence factors”, namely: Density, Compression, Flowability, Particle Size and Stability (Aguilar-Díaz et al., 2014). The aim of this work was to investigate mannitol- and lactose-based co-processed excipients, based on SeDeM Expert System methodology, and assess its suitability for compressible formulation development. ... | sr |
dc.language.iso | en | sr |
dc.publisher | Macedonian Pharmaceutical Association | sr |
dc.publisher | Faculty of Pharmacy, Ss Cyril and Methodius University in Skopje | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200161/RS// | sr |
dc.rights | openAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Macedonian Pharmaceutical Bulletin | sr |
dc.title | Applicability of Expert System for Drug Development as a tool for co-processed excipients formulation development | sr |
dc.type | conferenceObject | sr |
dc.rights.license | BY | sr |
dc.citation.volume | 68 | |
dc.citation.issue | Suppl 1 | |
dc.citation.spage | 223 | |
dc.citation.epage | 224 | |
dc.description.other | Seventh Congress of Pharmacy in North Macedonia with International participation, Ohrid, October 5-9, 2022. | sr |
dc.identifier.doi | 10.33320/maced.pharm.bull.2022.68.03.106 | |
dc.identifier.fulltext | http://farfar.pharmacy.bg.ac.rs/bitstream/id/14888/Applicability_of_expert_pub_2022.pdf | |
dc.type.version | publishedVersion | sr |