A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid Using Carbon Paste/Copper Schiff Base Composite Electrode
Само за регистроване кориснике
2023
Аутори
Kulizić, MihajloStanković, Milan
Rašić, Marija
Mijatović, Aleksandar
Baošić, Rada
Lolić, Aleksandar
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In this paper, a simple, sensitive, and precise flow injection system was optimized and applied to ascorbic acid determination with a carbon paste electrode modified with the Schiff base copper complex. The modified sensor showed increased sensitivity toward ascorbic acid oxidation with a decrease of oxidation potential by 200 mV. Under optimized flow parameters, working potential, gasket thickness, sample and reaction coil volumes, and flow rate, the developed flow system gave a linear response from 5 to 75 μmol/L of ascorbic acid. The calculated limit of detection was 4.5 μmol/L, calculated as 3σ/s which corresponds to the absolute value of 40 ng for the 50 μL sample coil. The precision for six consecutive injections of 5 and 75 μmol/L ascorbic acid solutions was determined as a relative standard deviation of 5.8 % and 1.5 %, respectively. The flow injection system enabled up to 120 analyses per hour. An optimized flow system was applied to the determination of ascorbic acid in dieta...ry supplements, after simple preparation.
Кључне речи:
amperometry / ascorbic acid / dietary supplements / flow injection analysis / modified carbon paste electrodeИзвор:
ChemistrySelect, 2023, 8, 48Издавач:
- John Wiley and Sons Inc
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200126 (Универзитет у Београду, Рударско-геолошки факултет) (RS-MESTD-inst-2020-200126)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200168 (Универзитет у Београду, Хемијски факултет) (RS-MESTD-inst-2020-200168)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200288 (Иновациони центар Хемијског факултета у Београду доо) (RS-MESTD-inst-2020-200288)
DOI: 10.1002/slct.202304631
ISSN: 2365-6549
WoS: 001128220300001
Scopus: 2-s2.0-85180196093
Институција/група
PharmacyTY - JOUR AU - Kulizić, Mihajlo AU - Stanković, Milan AU - Rašić, Marija AU - Mijatović, Aleksandar AU - Baošić, Rada AU - Lolić, Aleksandar PY - 2023 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5406 AB - In this paper, a simple, sensitive, and precise flow injection system was optimized and applied to ascorbic acid determination with a carbon paste electrode modified with the Schiff base copper complex. The modified sensor showed increased sensitivity toward ascorbic acid oxidation with a decrease of oxidation potential by 200 mV. Under optimized flow parameters, working potential, gasket thickness, sample and reaction coil volumes, and flow rate, the developed flow system gave a linear response from 5 to 75 μmol/L of ascorbic acid. The calculated limit of detection was 4.5 μmol/L, calculated as 3σ/s which corresponds to the absolute value of 40 ng for the 50 μL sample coil. The precision for six consecutive injections of 5 and 75 μmol/L ascorbic acid solutions was determined as a relative standard deviation of 5.8 % and 1.5 %, respectively. The flow injection system enabled up to 120 analyses per hour. An optimized flow system was applied to the determination of ascorbic acid in dietary supplements, after simple preparation. PB - John Wiley and Sons Inc T2 - ChemistrySelect T1 - A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid Using Carbon Paste/Copper Schiff Base Composite Electrode VL - 8 IS - 48 DO - 10.1002/slct.202304631 ER -
@article{ author = "Kulizić, Mihajlo and Stanković, Milan and Rašić, Marija and Mijatović, Aleksandar and Baošić, Rada and Lolić, Aleksandar", year = "2023", abstract = "In this paper, a simple, sensitive, and precise flow injection system was optimized and applied to ascorbic acid determination with a carbon paste electrode modified with the Schiff base copper complex. The modified sensor showed increased sensitivity toward ascorbic acid oxidation with a decrease of oxidation potential by 200 mV. Under optimized flow parameters, working potential, gasket thickness, sample and reaction coil volumes, and flow rate, the developed flow system gave a linear response from 5 to 75 μmol/L of ascorbic acid. The calculated limit of detection was 4.5 μmol/L, calculated as 3σ/s which corresponds to the absolute value of 40 ng for the 50 μL sample coil. The precision for six consecutive injections of 5 and 75 μmol/L ascorbic acid solutions was determined as a relative standard deviation of 5.8 % and 1.5 %, respectively. The flow injection system enabled up to 120 analyses per hour. An optimized flow system was applied to the determination of ascorbic acid in dietary supplements, after simple preparation.", publisher = "John Wiley and Sons Inc", journal = "ChemistrySelect", title = "A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid Using Carbon Paste/Copper Schiff Base Composite Electrode", volume = "8", number = "48", doi = "10.1002/slct.202304631" }
Kulizić, M., Stanković, M., Rašić, M., Mijatović, A., Baošić, R.,& Lolić, A.. (2023). A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid Using Carbon Paste/Copper Schiff Base Composite Electrode. in ChemistrySelect John Wiley and Sons Inc., 8(48). https://doi.org/10.1002/slct.202304631
Kulizić M, Stanković M, Rašić M, Mijatović A, Baošić R, Lolić A. A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid Using Carbon Paste/Copper Schiff Base Composite Electrode. in ChemistrySelect. 2023;8(48). doi:10.1002/slct.202304631 .
Kulizić, Mihajlo, Stanković, Milan, Rašić, Marija, Mijatović, Aleksandar, Baošić, Rada, Lolić, Aleksandar, "A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid Using Carbon Paste/Copper Schiff Base Composite Electrode" in ChemistrySelect, 8, no. 48 (2023), https://doi.org/10.1002/slct.202304631 . .