Electrochemical oxidation and interaction of newly synthesized acridine derivatives with DNA
Аутори
Rupar, JelenaAleksić, Mara
Dobričić, Vladimir
Čudina, Olivera
Brborić, Jasmina
Gavrilov, Nemanja
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Oxidation of newly synthesized acridine derivatives was studied using cyclic voltammetry at glassy
carbon electrode. Oxidation occurs as irreversible, diffusion-controlled process at pH 4.6 for
compounds 1-3 and as adsorption controlled process for compound 4. The interaction between newly
synthesized acridine compounds (compounds 1-4) and dsDNA was studied using a multilayer dsDNA
biosensor applying square wave voltammetry. Peak current corresponding to deoxyadenosine
decreased after 30 minutes of interaction suggesting interaction with dsDNA.
Извор:
Physical Chemistry 2021 (Proceedings), 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021. Belgrade, Serbia, 2021, I, 294-297Издавач:
- Society of Physical Chemists of Serbia
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200161 (Универзитет у Београду, Фармацеутски факултет) (RS-MESTD-inst-2020-200161)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200146 (Универзитет у Београду, Факултет за физичку хемију) (RS-MESTD-inst-2020-200146)
- RatioCAT - Rational Design of Multifunctional Electrode Interfaces for Efficient Electrocatalytic Hydrogen Production (RS-ScienceFundRS-Promis-6062244)
Напомена:
- 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021. Belgrade, Serbia
Институција/група
PharmacyTY - CONF AU - Rupar, Jelena AU - Aleksić, Mara AU - Dobričić, Vladimir AU - Čudina, Olivera AU - Brborić, Jasmina AU - Gavrilov, Nemanja PY - 2021 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5482 AB - Oxidation of newly synthesized acridine derivatives was studied using cyclic voltammetry at glassy carbon electrode. Oxidation occurs as irreversible, diffusion-controlled process at pH 4.6 for compounds 1-3 and as adsorption controlled process for compound 4. The interaction between newly synthesized acridine compounds (compounds 1-4) and dsDNA was studied using a multilayer dsDNA biosensor applying square wave voltammetry. Peak current corresponding to deoxyadenosine decreased after 30 minutes of interaction suggesting interaction with dsDNA. PB - Society of Physical Chemists of Serbia C3 - Physical Chemistry 2021 (Proceedings), 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021. Belgrade, Serbia T1 - Electrochemical oxidation and interaction of newly synthesized acridine derivatives with DNA VL - I SP - 294 EP - 297 UR - https://hdl.handle.net/21.15107/rcub_farfar_5482 ER -
@conference{ author = "Rupar, Jelena and Aleksić, Mara and Dobričić, Vladimir and Čudina, Olivera and Brborić, Jasmina and Gavrilov, Nemanja", year = "2021", abstract = "Oxidation of newly synthesized acridine derivatives was studied using cyclic voltammetry at glassy carbon electrode. Oxidation occurs as irreversible, diffusion-controlled process at pH 4.6 for compounds 1-3 and as adsorption controlled process for compound 4. The interaction between newly synthesized acridine compounds (compounds 1-4) and dsDNA was studied using a multilayer dsDNA biosensor applying square wave voltammetry. Peak current corresponding to deoxyadenosine decreased after 30 minutes of interaction suggesting interaction with dsDNA.", publisher = "Society of Physical Chemists of Serbia", journal = "Physical Chemistry 2021 (Proceedings), 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021. Belgrade, Serbia", title = "Electrochemical oxidation and interaction of newly synthesized acridine derivatives with DNA", volume = "I", pages = "294-297", url = "https://hdl.handle.net/21.15107/rcub_farfar_5482" }
Rupar, J., Aleksić, M., Dobričić, V., Čudina, O., Brborić, J.,& Gavrilov, N.. (2021). Electrochemical oxidation and interaction of newly synthesized acridine derivatives with DNA. in Physical Chemistry 2021 (Proceedings), 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021. Belgrade, Serbia Society of Physical Chemists of Serbia., I, 294-297. https://hdl.handle.net/21.15107/rcub_farfar_5482
Rupar J, Aleksić M, Dobričić V, Čudina O, Brborić J, Gavrilov N. Electrochemical oxidation and interaction of newly synthesized acridine derivatives with DNA. in Physical Chemistry 2021 (Proceedings), 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021. Belgrade, Serbia. 2021;I:294-297. https://hdl.handle.net/21.15107/rcub_farfar_5482 .
Rupar, Jelena, Aleksić, Mara, Dobričić, Vladimir, Čudina, Olivera, Brborić, Jasmina, Gavrilov, Nemanja, "Electrochemical oxidation and interaction of newly synthesized acridine derivatives with DNA" in Physical Chemistry 2021 (Proceedings), 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021. Belgrade, Serbia, I (2021):294-297, https://hdl.handle.net/21.15107/rcub_farfar_5482 .