Synthesis of hydantoins from N-Boc protected aminoacid derived amides using polymer-supported PPh3/CBr4as a reagent
Само за регистроване кориснике
2024
Аутори
Tasić, GordanaMitrović, Nikola
Simić, Milena
Koravović, Mladen
Jovanović, Predrag
Petković, Miloš
Jovanović, Miloš
Ivković, Branka
Savić, Vladimir
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Hydantoin derivatives are versatile structural motifs found in natural products
and various compounds with different biological or other properties. Due to
their importance in both organic and medicinal chemistry, a number of synthetic procedures have been developed. In this article, a novel methodology
utilizing N-Boc protected amino acid amides for their preparation has been
described. The cyclisation process was accomplished using solid supported
PPh3 and CBr 4 as reagents affording substituted hydantoins in moderate to
good yields (40%–77%).
Извор:
Journal Heterocyclic Chemistry, 2024Издавач:
- Wiley Periodicals LLC.
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200161 (Универзитет у Београду, Фармацеутски факултет) (RS-MESTD-inst-2020-200161)
DOI: 10.1002/jhet.4802
ISSN: 0022-152X
WoS: 001181439100001
Scopus: 2-s2.0-85187113166
Институција/група
PharmacyTY - JOUR AU - Tasić, Gordana AU - Mitrović, Nikola AU - Simić, Milena AU - Koravović, Mladen AU - Jovanović, Predrag AU - Petković, Miloš AU - Jovanović, Miloš AU - Ivković, Branka AU - Savić, Vladimir PY - 2024 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5556 AB - Hydantoin derivatives are versatile structural motifs found in natural products and various compounds with different biological or other properties. Due to their importance in both organic and medicinal chemistry, a number of synthetic procedures have been developed. In this article, a novel methodology utilizing N-Boc protected amino acid amides for their preparation has been described. The cyclisation process was accomplished using solid supported PPh3 and CBr 4 as reagents affording substituted hydantoins in moderate to good yields (40%–77%). PB - Wiley Periodicals LLC. T2 - Journal Heterocyclic Chemistry T1 - Synthesis of hydantoins from N-Boc protected aminoacid derived amides using polymer-supported PPh3/CBr4as a reagent DO - 10.1002/jhet.4802 ER -
@article{ author = "Tasić, Gordana and Mitrović, Nikola and Simić, Milena and Koravović, Mladen and Jovanović, Predrag and Petković, Miloš and Jovanović, Miloš and Ivković, Branka and Savić, Vladimir", year = "2024", abstract = "Hydantoin derivatives are versatile structural motifs found in natural products and various compounds with different biological or other properties. Due to their importance in both organic and medicinal chemistry, a number of synthetic procedures have been developed. In this article, a novel methodology utilizing N-Boc protected amino acid amides for their preparation has been described. The cyclisation process was accomplished using solid supported PPh3 and CBr 4 as reagents affording substituted hydantoins in moderate to good yields (40%–77%).", publisher = "Wiley Periodicals LLC.", journal = "Journal Heterocyclic Chemistry", title = "Synthesis of hydantoins from N-Boc protected aminoacid derived amides using polymer-supported PPh3/CBr4as a reagent", doi = "10.1002/jhet.4802" }
Tasić, G., Mitrović, N., Simić, M., Koravović, M., Jovanović, P., Petković, M., Jovanović, M., Ivković, B.,& Savić, V.. (2024). Synthesis of hydantoins from N-Boc protected aminoacid derived amides using polymer-supported PPh3/CBr4as a reagent. in Journal Heterocyclic Chemistry Wiley Periodicals LLC... https://doi.org/10.1002/jhet.4802
Tasić G, Mitrović N, Simić M, Koravović M, Jovanović P, Petković M, Jovanović M, Ivković B, Savić V. Synthesis of hydantoins from N-Boc protected aminoacid derived amides using polymer-supported PPh3/CBr4as a reagent. in Journal Heterocyclic Chemistry. 2024;. doi:10.1002/jhet.4802 .
Tasić, Gordana, Mitrović, Nikola, Simić, Milena, Koravović, Mladen, Jovanović, Predrag, Petković, Miloš, Jovanović, Miloš, Ivković, Branka, Savić, Vladimir, "Synthesis of hydantoins from N-Boc protected aminoacid derived amides using polymer-supported PPh3/CBr4as a reagent" in Journal Heterocyclic Chemistry (2024), https://doi.org/10.1002/jhet.4802 . .