The impact of the aqueous phase on the physicochemical characteristics of nanoemulsions loaded with patent protected compound GL-II-73
Само за регистроване кориснике
2024
Аутори
Đoković, JelenaNikolić, Ines
Sharmin, Dishary
Cook, James M.
Savić, Miroslav
Borchard, Gerrit
Savić, Snežana
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
INTRODUCTION Temporal lobe epilepsy is characterized by seizures, but can also be associated with mental health problems for which there are no clear treatment regimens. A proprietary compound, GL-II-73 - (4R)-8-ethynyl-6-(2-fluorophenyl)-N,N,4-trimethyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxamide, a positive allosteric modulator of α5-containing γ-aminobutyric acid (GABA) receptors, has been shown to be effective in the treatment of these comorbidities [1]. ...
Кључне речи:
GL-II-73 / parenteral nanoemulsion / orthogonal techiques / aqueous phase of nanoemulsionsИзвор:
14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria, 2024Издавач:
- International Society of Drug Delivery Sciences and Technology (APGI)
- International Association for Pharmaceutical Technology (APV)
- Italian Society of Technology and Legislation (S.T.E.L.F)
Финансирање / пројекти:
- NanoCellEmoCog - Neuroimmune aspects of mood, anxiety and cognitive effects of leads/drug candidates acting at GABAA and/or sigma-2 receptors: In vitro/in vivo delineation by nano- and hiPSC-based platform (RS-ScienceFundRS-Ideje-7749108)
Институција/група
PharmacyTY - CONF AU - Đoković, Jelena AU - Nikolić, Ines AU - Sharmin, Dishary AU - Cook, James M. AU - Savić, Miroslav AU - Borchard, Gerrit AU - Savić, Snežana PY - 2024 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5575 AB - INTRODUCTION Temporal lobe epilepsy is characterized by seizures, but can also be associated with mental health problems for which there are no clear treatment regimens. A proprietary compound, GL-II-73 - (4R)-8-ethynyl-6-(2-fluorophenyl)-N,N,4-trimethyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxamide, a positive allosteric modulator of α5-containing γ-aminobutyric acid (GABA) receptors, has been shown to be effective in the treatment of these comorbidities [1]. ... PB - International Society of Drug Delivery Sciences and Technology (APGI) PB - International Association for Pharmaceutical Technology (APV) PB - Italian Society of Technology and Legislation (S.T.E.L.F) C3 - 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria T1 - The impact of the aqueous phase on the physicochemical characteristics of nanoemulsions loaded with patent protected compound GL-II-73 UR - https://hdl.handle.net/21.15107/rcub_farfar_5575 ER -
@conference{ author = "Đoković, Jelena and Nikolić, Ines and Sharmin, Dishary and Cook, James M. and Savić, Miroslav and Borchard, Gerrit and Savić, Snežana", year = "2024", abstract = "INTRODUCTION Temporal lobe epilepsy is characterized by seizures, but can also be associated with mental health problems for which there are no clear treatment regimens. A proprietary compound, GL-II-73 - (4R)-8-ethynyl-6-(2-fluorophenyl)-N,N,4-trimethyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxamide, a positive allosteric modulator of α5-containing γ-aminobutyric acid (GABA) receptors, has been shown to be effective in the treatment of these comorbidities [1]. ...", publisher = "International Society of Drug Delivery Sciences and Technology (APGI), International Association for Pharmaceutical Technology (APV), Italian Society of Technology and Legislation (S.T.E.L.F)", journal = "14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria", title = "The impact of the aqueous phase on the physicochemical characteristics of nanoemulsions loaded with patent protected compound GL-II-73", url = "https://hdl.handle.net/21.15107/rcub_farfar_5575" }
Đoković, J., Nikolić, I., Sharmin, D., Cook, J. M., Savić, M., Borchard, G.,& Savić, S.. (2024). The impact of the aqueous phase on the physicochemical characteristics of nanoemulsions loaded with patent protected compound GL-II-73. in 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria International Society of Drug Delivery Sciences and Technology (APGI).. https://hdl.handle.net/21.15107/rcub_farfar_5575
Đoković J, Nikolić I, Sharmin D, Cook JM, Savić M, Borchard G, Savić S. The impact of the aqueous phase on the physicochemical characteristics of nanoemulsions loaded with patent protected compound GL-II-73. in 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria. 2024;. https://hdl.handle.net/21.15107/rcub_farfar_5575 .
Đoković, Jelena, Nikolić, Ines, Sharmin, Dishary, Cook, James M., Savić, Miroslav, Borchard, Gerrit, Savić, Snežana, "The impact of the aqueous phase on the physicochemical characteristics of nanoemulsions loaded with patent protected compound GL-II-73" in 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria (2024), https://hdl.handle.net/21.15107/rcub_farfar_5575 .