Antimicrobial and Cytotoxic Activities of Essential Oil from the Aerial Parts of Pulicaria dysenterica (L.) Bernh. (Asteraceae)
Аутори
Cilović Kozarević, ErminaDautović, Esmeralda
Halilčević, Dalila
Kolarević, Lamija
Šarić-Kundalić, Broza
Karić, Enida
Smajlagić, Aida
Husejnagić, Darja
Horozić, Emir
Glamočlija, Jasmina
Soković, Marina
Arsenijević, Jelena
Maksimović, Zoran
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The chemical composition of Pulicaria dysenterica (L.) Bernh. aerial parts essential oil (EO), growing wild in Bosnia and Herzegovina, was presented in the study. In addition to the EO composition, antimicrobial and cytotoxic activities were also tested. The aerial parts of P. dysenterica contained 0.3% of yellow, liquid, fragrant EO. The 51 components identified accounted for 81.09% of the oil. The EO was characterized by the presence of a high concentration of oxygenated sesquiterpenes 51.83% while oxygenated monoterpenes constituted 15.57%, sesquiterpene hydrocarbons 9.32% and non-terpene compounds presented 4.37% of the EO. The dominant compounds were the sesquiterpenes caryophyllene oxide, (E)-nerolidol, β-caryophyllene and monoterpene nerol. The antimicrobial activity of EO was tested against selected ATCC strains of microorganisms, the bacteria Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, and the fungus Candida albicans. The results showed that the investi...gated EO inhibited the growth of all selected ATCC strains of microorganisms. The best result was obtained against Escherichia coli bacteria with MIC value of 1 mgmL-1. The cytotoxicity of EO was measured against the HeLa cell line using the MTT method with IC50 of 188.52 μgmL-1. This study has provided scientific baseline data on the therapeutic properties of P. dysenterica.
Кључне речи:
Pulicaria dysenterica / essential oil / antimicrobial activity / cytotoxicityИзвор:
Technologica Acta, 2024, 16, 2, 81-86Издавач:
- Faculty of Technology, University in Tuzla
Финансирање / пројекти:
- Federal Ministry of Education and Science (FB&H).
Институција/група
PharmacyTY - JOUR AU - Cilović Kozarević, Ermina AU - Dautović, Esmeralda AU - Halilčević, Dalila AU - Kolarević, Lamija AU - Šarić-Kundalić, Broza AU - Karić, Enida AU - Smajlagić, Aida AU - Husejnagić, Darja AU - Horozić, Emir AU - Glamočlija, Jasmina AU - Soković, Marina AU - Arsenijević, Jelena AU - Maksimović, Zoran PY - 2024 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5635 AB - The chemical composition of Pulicaria dysenterica (L.) Bernh. aerial parts essential oil (EO), growing wild in Bosnia and Herzegovina, was presented in the study. In addition to the EO composition, antimicrobial and cytotoxic activities were also tested. The aerial parts of P. dysenterica contained 0.3% of yellow, liquid, fragrant EO. The 51 components identified accounted for 81.09% of the oil. The EO was characterized by the presence of a high concentration of oxygenated sesquiterpenes 51.83% while oxygenated monoterpenes constituted 15.57%, sesquiterpene hydrocarbons 9.32% and non-terpene compounds presented 4.37% of the EO. The dominant compounds were the sesquiterpenes caryophyllene oxide, (E)-nerolidol, β-caryophyllene and monoterpene nerol. The antimicrobial activity of EO was tested against selected ATCC strains of microorganisms, the bacteria Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, and the fungus Candida albicans. The results showed that the investigated EO inhibited the growth of all selected ATCC strains of microorganisms. The best result was obtained against Escherichia coli bacteria with MIC value of 1 mgmL-1. The cytotoxicity of EO was measured against the HeLa cell line using the MTT method with IC50 of 188.52 μgmL-1. This study has provided scientific baseline data on the therapeutic properties of P. dysenterica. PB - Faculty of Technology, University in Tuzla T2 - Technologica Acta T1 - Antimicrobial and Cytotoxic Activities of Essential Oil from the Aerial Parts of Pulicaria dysenterica (L.) Bernh. (Asteraceae) VL - 16 IS - 2 SP - 81 EP - 86 DO - 10.51558/2232-7568.2023.16.2.81 ER -
@article{ author = "Cilović Kozarević, Ermina and Dautović, Esmeralda and Halilčević, Dalila and Kolarević, Lamija and Šarić-Kundalić, Broza and Karić, Enida and Smajlagić, Aida and Husejnagić, Darja and Horozić, Emir and Glamočlija, Jasmina and Soković, Marina and Arsenijević, Jelena and Maksimović, Zoran", year = "2024", abstract = "The chemical composition of Pulicaria dysenterica (L.) Bernh. aerial parts essential oil (EO), growing wild in Bosnia and Herzegovina, was presented in the study. In addition to the EO composition, antimicrobial and cytotoxic activities were also tested. The aerial parts of P. dysenterica contained 0.3% of yellow, liquid, fragrant EO. The 51 components identified accounted for 81.09% of the oil. The EO was characterized by the presence of a high concentration of oxygenated sesquiterpenes 51.83% while oxygenated monoterpenes constituted 15.57%, sesquiterpene hydrocarbons 9.32% and non-terpene compounds presented 4.37% of the EO. The dominant compounds were the sesquiterpenes caryophyllene oxide, (E)-nerolidol, β-caryophyllene and monoterpene nerol. The antimicrobial activity of EO was tested against selected ATCC strains of microorganisms, the bacteria Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, and the fungus Candida albicans. The results showed that the investigated EO inhibited the growth of all selected ATCC strains of microorganisms. The best result was obtained against Escherichia coli bacteria with MIC value of 1 mgmL-1. The cytotoxicity of EO was measured against the HeLa cell line using the MTT method with IC50 of 188.52 μgmL-1. This study has provided scientific baseline data on the therapeutic properties of P. dysenterica.", publisher = "Faculty of Technology, University in Tuzla", journal = "Technologica Acta", title = "Antimicrobial and Cytotoxic Activities of Essential Oil from the Aerial Parts of Pulicaria dysenterica (L.) Bernh. (Asteraceae)", volume = "16", number = "2", pages = "81-86", doi = "10.51558/2232-7568.2023.16.2.81" }
Cilović Kozarević, E., Dautović, E., Halilčević, D., Kolarević, L., Šarić-Kundalić, B., Karić, E., Smajlagić, A., Husejnagić, D., Horozić, E., Glamočlija, J., Soković, M., Arsenijević, J.,& Maksimović, Z.. (2024). Antimicrobial and Cytotoxic Activities of Essential Oil from the Aerial Parts of Pulicaria dysenterica (L.) Bernh. (Asteraceae). in Technologica Acta Faculty of Technology, University in Tuzla., 16(2), 81-86. https://doi.org/10.51558/2232-7568.2023.16.2.81
Cilović Kozarević E, Dautović E, Halilčević D, Kolarević L, Šarić-Kundalić B, Karić E, Smajlagić A, Husejnagić D, Horozić E, Glamočlija J, Soković M, Arsenijević J, Maksimović Z. Antimicrobial and Cytotoxic Activities of Essential Oil from the Aerial Parts of Pulicaria dysenterica (L.) Bernh. (Asteraceae). in Technologica Acta. 2024;16(2):81-86. doi:10.51558/2232-7568.2023.16.2.81 .
Cilović Kozarević, Ermina, Dautović, Esmeralda, Halilčević, Dalila, Kolarević, Lamija, Šarić-Kundalić, Broza, Karić, Enida, Smajlagić, Aida, Husejnagić, Darja, Horozić, Emir, Glamočlija, Jasmina, Soković, Marina, Arsenijević, Jelena, Maksimović, Zoran, "Antimicrobial and Cytotoxic Activities of Essential Oil from the Aerial Parts of Pulicaria dysenterica (L.) Bernh. (Asteraceae)" in Technologica Acta, 16, no. 2 (2024):81-86, https://doi.org/10.51558/2232-7568.2023.16.2.81 . .