Antioxidant Activity of Yellow Dock (Rumex crispus L., Polygonaceae) Fruit Extract
Само за регистроване кориснике
2011
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The methanol extract of ripe Rumex crispus L. fruits was evaluated for its antioxidant potential by assays for ferric-reducing antioxidant power (FRAP), DPPH-free radical scavenging activity (DPPH) and the influence on lipid peroxidation in liposomes (LP). Considerable activity was observed in all test systems (FRAP: 9.9 mmol Fe2+/g; DPPH IC50: 3.7 mu g/mL; LP IC50: 4.9 mu g/mL), comparable to that of BHT (FRAP: 8.0 mu g/mL; DPPH IC50: 19.4 mu g/mL; LP IC50: 3.5 mu g/mL), but lower than the activity of ascorbic acid, rutin and quercetin, used as positive control substances. The in vivo effects were evaluated in several hepatic antioxidant systems (activities of LPx, GSH-Px, Px, CAT and XOD, as well as GSH content), after treatment with the studied yellow dock extract in different doses, or in combination with carbon tetrachloride (CCl4). Pretreatment with the R. crispus extract inhibited CCl4-induced oxidative stress by decreasing LPx and increasing GSH content in a dose dependent mann...er, bringing the levels of antioxidant enzymes to near control values. Copyright
Кључне речи:
Rumex crispus L. / antioxidant activity / ferric-reducing antioxidant power / DPPH free radical scavenging activity / lipid peroxidationИзвор:
Phytotherapy Research, 2011, 25, 1, 101-105Издавач:
- Wiley, Hoboken
Финансирање / пројекти:
- Испитивање лековитог потенцијала биљака: морфолошка, хемијска и фармаколошка карактеризација (RS-143012)
DOI: 10.1002/ptr.3234
ISSN: 0951-418X
PubMed: 20623623
WoS: 000285848700016
Scopus: 2-s2.0-78650635774
Институција/група
PharmacyTY - JOUR AU - Maksimović, Zoran AU - Kovačević, Nada AU - Lakušić, Branislava AU - Cebović, Tatjana PY - 2011 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1535 AB - The methanol extract of ripe Rumex crispus L. fruits was evaluated for its antioxidant potential by assays for ferric-reducing antioxidant power (FRAP), DPPH-free radical scavenging activity (DPPH) and the influence on lipid peroxidation in liposomes (LP). Considerable activity was observed in all test systems (FRAP: 9.9 mmol Fe2+/g; DPPH IC50: 3.7 mu g/mL; LP IC50: 4.9 mu g/mL), comparable to that of BHT (FRAP: 8.0 mu g/mL; DPPH IC50: 19.4 mu g/mL; LP IC50: 3.5 mu g/mL), but lower than the activity of ascorbic acid, rutin and quercetin, used as positive control substances. The in vivo effects were evaluated in several hepatic antioxidant systems (activities of LPx, GSH-Px, Px, CAT and XOD, as well as GSH content), after treatment with the studied yellow dock extract in different doses, or in combination with carbon tetrachloride (CCl4). Pretreatment with the R. crispus extract inhibited CCl4-induced oxidative stress by decreasing LPx and increasing GSH content in a dose dependent manner, bringing the levels of antioxidant enzymes to near control values. Copyright PB - Wiley, Hoboken T2 - Phytotherapy Research T1 - Antioxidant Activity of Yellow Dock (Rumex crispus L., Polygonaceae) Fruit Extract VL - 25 IS - 1 SP - 101 EP - 105 DO - 10.1002/ptr.3234 ER -
@article{ author = "Maksimović, Zoran and Kovačević, Nada and Lakušić, Branislava and Cebović, Tatjana", year = "2011", abstract = "The methanol extract of ripe Rumex crispus L. fruits was evaluated for its antioxidant potential by assays for ferric-reducing antioxidant power (FRAP), DPPH-free radical scavenging activity (DPPH) and the influence on lipid peroxidation in liposomes (LP). Considerable activity was observed in all test systems (FRAP: 9.9 mmol Fe2+/g; DPPH IC50: 3.7 mu g/mL; LP IC50: 4.9 mu g/mL), comparable to that of BHT (FRAP: 8.0 mu g/mL; DPPH IC50: 19.4 mu g/mL; LP IC50: 3.5 mu g/mL), but lower than the activity of ascorbic acid, rutin and quercetin, used as positive control substances. The in vivo effects were evaluated in several hepatic antioxidant systems (activities of LPx, GSH-Px, Px, CAT and XOD, as well as GSH content), after treatment with the studied yellow dock extract in different doses, or in combination with carbon tetrachloride (CCl4). Pretreatment with the R. crispus extract inhibited CCl4-induced oxidative stress by decreasing LPx and increasing GSH content in a dose dependent manner, bringing the levels of antioxidant enzymes to near control values. Copyright", publisher = "Wiley, Hoboken", journal = "Phytotherapy Research", title = "Antioxidant Activity of Yellow Dock (Rumex crispus L., Polygonaceae) Fruit Extract", volume = "25", number = "1", pages = "101-105", doi = "10.1002/ptr.3234" }
Maksimović, Z., Kovačević, N., Lakušić, B.,& Cebović, T.. (2011). Antioxidant Activity of Yellow Dock (Rumex crispus L., Polygonaceae) Fruit Extract. in Phytotherapy Research Wiley, Hoboken., 25(1), 101-105. https://doi.org/10.1002/ptr.3234
Maksimović Z, Kovačević N, Lakušić B, Cebović T. Antioxidant Activity of Yellow Dock (Rumex crispus L., Polygonaceae) Fruit Extract. in Phytotherapy Research. 2011;25(1):101-105. doi:10.1002/ptr.3234 .
Maksimović, Zoran, Kovačević, Nada, Lakušić, Branislava, Cebović, Tatjana, "Antioxidant Activity of Yellow Dock (Rumex crispus L., Polygonaceae) Fruit Extract" in Phytotherapy Research, 25, no. 1 (2011):101-105, https://doi.org/10.1002/ptr.3234 . .