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Development and validation of liquid chromatography method for the separation of valdecoxib and its SC-77852 impurity
(Taylor & Francis Inc, Philadelphia, 2006)
A reversed-phase liquid chromatography method has been developed for the separation of valdecoxib and impurity SC-77852. The best results were achieved using a mobile phase-methanol: 1% water solution TEA (52 : 48 v/v), ...
Composition of essential oil of Artemisia campestris L. from Serbia
(Taylor & Francis Inc, Philadelphia, 2003)
The essential oil yield from the aerial parts of A. campestris was 0.2% (mL/g dried plant). The oil was analyzed using GC and GUMS and 38 compounds were identified. The principal components were sesquiterpene alcohols: ...
Independent association of high serum uric acid concentration with angiographically defined coronary artery disease
(Tohoku Univ Medical Press, Sendai, 2007)
Epidemiological studies have shown that a high serum uric acid concentration is a risk factor for coronary artery disease (CAD). However, the issue of whether it is an independent cardiovascular risk factor or simply a ...
Influence of β cyclodextrin on the crystallinity and dissolution rate of carbamazepine polymorphs
(Slovenian Pharmaceutical Society, 2003)
Guidelines for the use of tumor markers in breast cancer / Vodiči za primenu tumorskih markera kod karcinoma dojke
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2007)
The best-validated markers in breast cancer are all tissue based and include estrogen receptors (ER), progesteron receptors (PR), HER-2, urokinase plasminogen activator (uPA) and plasminogen activator inhibitor 1 (PAI-1). ...
Effect of magnesium pretreatment on reduced glutathione levels in tissues of mice exposed to acute and subacute cadmium intoxication: a time course study
(John Libbey Eurotext Ltd, Montrouge, 2007)
The study was designed to investigate the role of magnesium (Mg) pretreatment on reduced glutathione (GSH) levels in kidney, liver and testis of mice intoxicated with cadmium (Cd). Animals were divided into four groups: I ...
Drugs affecting the renin-angiotensinaldosterone system and ischemic heart disease / Lekovi koji utiču na aktivnost sistema renin-angiotenzin-aldosteron i ishemijska bolest srca
(Savez farmaceutskih udruženja Srbije, Beograd, 2008)
The renin-angiotensin-aldosterone (RAAS) system is a multilayered cascade of mediators involved in regulation of arterial pressure, tissue perfusion and extracellular volume, and hence the cardiovascular and renal homeostasis. ...
Natural substances that may cause addiction / Jedinjenja prirodnog porekla koja stvaraju zavisnost - narkomanija
(Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd, 2008)
The term addiction is used in many contexts. It is not limited to substance abuse and can be applied to any activity characterized by compulsion, loss of control and continuation of the substance despite harm. Some researchers ...
Antioxidative effect of nerve growth factor (NGF) in rat thalamus after quinolinic acid-induced neurotoxicity / Efekat NGF na antioksidativnu odbranu u talamusu pacova nakon neurotoksičnog delovanja hinolinske kiseline
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Quinolinic acid (QA) produces a pattern of selective cell loss in the striatum, that closely mimics that of Huntington's disease (HD). The aim of this study was to investigate the antioxidative status in the thalamus after ...
Chromatographic methods in predicting oral drug absorption / Hromatografske metode za predviđanje apsorpcije leka posle oralne primene
(Savez farmaceutskih udruženja Srbije, Beograd, 2008)
Today with the development of combinatorial chemistry hundreds and hundreds of compounds that have potential biological activity are synthesized. The studies which include the selection of drug candidates and the study of ...