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Gradient Boosted Tree model: A fast track tool for predicting the Atmospheric Pressure Chemical Ionization-Mass Spectrometry signal of antipsychotics based on molecular features and experimental settings
(Elsevier B.V., 2022)
Predicting the response signal in Atmospheric Pressure Chemical Ionization - Mass Spectrometry (APCI-MS) systems appears to be considerably challenging due to a gap in knowledge of governing factors and nature of their ...
Optimization of the lyophilisation process for esomeprazole 40 mg powder for solution for injection/infusion using quality by design concept
(Elsevier, 2022)
The aim of this work was to apply the of Quality by Design concept in optimization of lyophilisation process in production of esomeprazole 40 mg powder for solution for injection/infusion. Optimization has been triggered ...
Generic approach in a gradient elution HPLC method development that enables troubleshooting free method transfer
(Elsevier B.V., 2022)
Nowadays, method development is strongly focused on reducing time needed for method development and execution. This subject specially concerns gradient elution methods regarding the usual need for trouble shooting assistance ...
Shared Decision Making
(Springer Science and Business Media Deutschland GmbH, 2022)
This chapter is divided into three sections. The first section introduces the concept and models of shared decision-making as a framework of person- centered care. The second section focuses on multicriteria decision-making ...
Toxic elements in children's crayons and colored pencils: Bioaccessibility assessment / Tоксични елементи у воштаним и дрвеним бојицама за децу: процена биодоступности
(Serbian Chemical Society, 2022)
Crayons and colored pencils for children may contain toxic elements (TEs) exhibiting potential risk for children’s health including cognitive development, after their ingestion, through mouthing and chewing and eventually, ...
The correlation between genetic factors and freezing of gait in patients with Parkinson's disease
(Elsevier Ltd, 2022)
Background: Clinical-related risk factors to freezing of gait (FOG) in Parkinson’s disease (PD) have been iden- tified. Still, the influence of genetic variations on the FOG occurrence has been poorly studied thus far. ...
CYP2C19 slow metabolizer phenotype is associated with lower antidepressant efficacy and tolerability
(Elsevier Ireland Ltd, 2022)
The inter-individual variability in CYP2C19-mediated metabolism may affect the antidepressant treatment. The aim of this study is to evaluate differences in antidepressant efficacy and tolerability between different CYP2C19 ...
Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients
(Croatian Society of Medical Biochemistry and Laboratory Medicine, 2022)
Introduction The aim of this study was to investigate lipoprotein particle distributions and the likelihood of achieving cholesterol homeostasis in the remission phase of nephrotic syndrome (NS) in paediatric patients. ...
Integrating moving average control procedures into the risk-based quality control plan in small-volume medical laboratories
(Croatian Society of Medical Biochemistry and Laboratory Medicine, 2022)
Introduction: The modern approach to quality control (QC) in medical laboratories implies the development of a risk-based control plan. This paper aims to develop a risk-based QC plan for a laboratory with a small daily ...
Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors
(Elsevier B.V., 2022)
Here, we propose a novel, electrochemical preparation of in situ N-doped alginate-based carbon precursors with monodispersed zinc ions. Obtained carbons were evaluated by spectroscopic (FTIR, Raman and XPS), textural (N2 ...